Conservative treatment of anal canal cancer: Retrospective study

M. L. Friso, L. Loreggian, C. Baiocchi, M. G. Cesaro, F. Berti, R. Mazzarotto, A. Fornasiero, F. Calzavara

Research output: Contribution to journalArticle


Between January 1981 and May 1996, thirty patients with anal canal carcinoma were treated with a protocol of radiation therapy alone or in combination with chemotherapy. The patients were divided into 4 stages by International Union against Cancer (UICC) 1987: I stage 8 patients, II stage 16 patients, III stage 5 patients, nobody in stage IV and 1 patient in recurrence. Sixteen patients were treated with external radiation therapy alone, 8 with interstitial 192Ir implant alone, and 6 with the combination of both (dose range 30-70 Gy). Nine patients received concomitant cytotoxic chemotherapy. Toxicities were mild to moderate. Twenty-eight patients were eligible and 2 were lost to follow-up. A complete response (CR) was observed in 19 patients (68%); nobody of these patients had local recurrence and anorectal function was retained. We may conclude that radiotherapy with or without chemotherapy can provide a good local control and preserve anal function with acceptable morbidity.

Original languageEnglish
Pages (from-to)215-217
Number of pages3
JournalRadiology and Oncology
Issue number2
Publication statusPublished - 1997


  • Rectal neoplasms-radiotherapy-drug therapy
  • Treatment outcome

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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    Friso, M. L., Loreggian, L., Baiocchi, C., Cesaro, M. G., Berti, F., Mazzarotto, R., Fornasiero, A., & Calzavara, F. (1997). Conservative treatment of anal canal cancer: Retrospective study. Radiology and Oncology, 31(2), 215-217.