Consideration on two cases of dystonia-parkinsonism

C. A. Zambrino, U. Balottin, R. Borgatti, G. Lanzi

Research output: Contribution to journalArticle

Abstract

We describe two sporadic cases of dystonia-parkinsonism at different stages of disease progression. The two girls, first seen at the ages of 10 and 12 years, have been followed for 9 and 2 years respectively. In both patients L-dopa 60 mg+carbidopa 6 mg brought about a swift remission of symptoms, which persists to date. All examinations, including CT and MR brainscans, were normal. The CSF and urine levels of HVA and 5 HIAA were low in one case and normalized with treatment. This finding might provide a fairly valid predictive index of responsiveness to L-dopa.

Original languageEnglish
Pages (from-to)475-478
Number of pages4
JournalItalian Journal of Neurological Sciences
Volume12
Issue number4
DOIs
Publication statusPublished - Aug 1991

Fingerprint

Dystonia
Parkinsonian Disorders
Levodopa
Carbidopa
Dystonic Disorders
Hydroxyindoleacetic Acid
Disease Progression
Urine
Therapeutics

Keywords

  • Dystonia-parkinsonism
  • follow-up
  • L-dopa treatment

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Consideration on two cases of dystonia-parkinsonism. / Zambrino, C. A.; Balottin, U.; Borgatti, R.; Lanzi, G.

In: Italian Journal of Neurological Sciences, Vol. 12, No. 4, 08.1991, p. 475-478.

Research output: Contribution to journalArticle

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