Abstract
Tyrosine hydroxylase (TH) was studied in the entire hypothalamus of 60-day-old male and female rats, and its activity was similar in both sexes. Administration of estrogen or androgen to male or female pups soon after birth and during development did not affect the kinetic parameters of TH. It is, thus, suggested that sexual dimorphism in the levels and turnover of catecholamines (CA) and their sensitivity to fluctuations in gonadal steroids during development do not depend on corresponding sex-related or steroid-sensitive differences in the synthesis of hypothalamic CA.
| Original language | English |
|---|---|
| Pages (from-to) | 21-25 |
| Number of pages | 5 |
| Journal | Journal of Neuroscience Research |
| Volume | 8 |
| Issue number | 1 |
| Publication status | Published - 1982 |
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ASJC Scopus subject areas
- Neuroscience(all)
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Constancy of adult hypothalamic tyrosine hydroxylase after gonadal steroid treatment during development. / Vaccari, A.; Biassoni, R.
In: Journal of Neuroscience Research, Vol. 8, No. 1, 1982, p. 21-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Constancy of adult hypothalamic tyrosine hydroxylase after gonadal steroid treatment during development
AU - Vaccari, A.
AU - Biassoni, R.
PY - 1982
Y1 - 1982
N2 - Tyrosine hydroxylase (TH) was studied in the entire hypothalamus of 60-day-old male and female rats, and its activity was similar in both sexes. Administration of estrogen or androgen to male or female pups soon after birth and during development did not affect the kinetic parameters of TH. It is, thus, suggested that sexual dimorphism in the levels and turnover of catecholamines (CA) and their sensitivity to fluctuations in gonadal steroids during development do not depend on corresponding sex-related or steroid-sensitive differences in the synthesis of hypothalamic CA.
AB - Tyrosine hydroxylase (TH) was studied in the entire hypothalamus of 60-day-old male and female rats, and its activity was similar in both sexes. Administration of estrogen or androgen to male or female pups soon after birth and during development did not affect the kinetic parameters of TH. It is, thus, suggested that sexual dimorphism in the levels and turnover of catecholamines (CA) and their sensitivity to fluctuations in gonadal steroids during development do not depend on corresponding sex-related or steroid-sensitive differences in the synthesis of hypothalamic CA.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019959924&partnerID=8YFLogxK
M3 - Article
C2 - 6129328
AN - SCOPUS:0019959924
VL - 8
SP - 21
EP - 25
JO - Journal of Neuroscience Research
JF - Journal of Neuroscience Research
SN - 0360-4012
IS - 1
ER -