TY - JOUR
T1 - Consumption of a highly palatable food induces a lasting place-conditioning memory in marmoset monkeys
AU - Duarte, R. B M
AU - Patrono, E.
AU - Borges, A. C.
AU - César, A. A S
AU - Tomaz, C.
AU - Ventura, R.
AU - Gasbarri, A.
AU - Puglisi-Allegra, S.
AU - Barros, M.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Highly palatible foods may induce addiction-related behaviors. However, this has yet to be established in non-human primates. Therefore, we evaluated whether marmoset monkeys ( Calllithrix penicillata) acquire a conditioned-place-preference (CPP) for chocolate and if this response is detectable after a 24-h and 15-day period. Subjects were first habituated to a two-compartment CPP box and then randomly assigned to a chocolate or control group. Thereafter, they were given access to only one compartment during daily 15-min conditionings, held on six consecutive days. On each trial, the chocolate group received pieces of chocolate (50. g) in this context, whereas controls were not given a food reward. Marmosets were subsequently tested for preferring this (food) paired context after a 24-h and 15-day interval. During conditioning, individual foraging and the amount of chocolate ingested by each pair of the chocolate group remained constant. However, compared to pre-CPP levels, the time spent inside/in contact with the conditioned compartment increased significantly, while the latency to first entry decreased on both post-CPP intervals. For controls, the parameters remained unaltered. Thus, chocolate induced a persistent CPP response-an aspect usually associated with drug-related rewards.
AB - Highly palatible foods may induce addiction-related behaviors. However, this has yet to be established in non-human primates. Therefore, we evaluated whether marmoset monkeys ( Calllithrix penicillata) acquire a conditioned-place-preference (CPP) for chocolate and if this response is detectable after a 24-h and 15-day period. Subjects were first habituated to a two-compartment CPP box and then randomly assigned to a chocolate or control group. Thereafter, they were given access to only one compartment during daily 15-min conditionings, held on six consecutive days. On each trial, the chocolate group received pieces of chocolate (50. g) in this context, whereas controls were not given a food reward. Marmosets were subsequently tested for preferring this (food) paired context after a 24-h and 15-day interval. During conditioning, individual foraging and the amount of chocolate ingested by each pair of the chocolate group remained constant. However, compared to pre-CPP levels, the time spent inside/in contact with the conditioned compartment increased significantly, while the latency to first entry decreased on both post-CPP intervals. For controls, the parameters remained unaltered. Thus, chocolate induced a persistent CPP response-an aspect usually associated with drug-related rewards.
KW - Chocolate
KW - Food reward
KW - Long-term memory
KW - Marmoset
KW - Place-conditioning
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UR - http://www.scopus.com/inward/citedby.url?scp=84908086796&partnerID=8YFLogxK
U2 - 10.1016/j.beproc.2014.08.021
DO - 10.1016/j.beproc.2014.08.021
M3 - Article
C2 - 25175712
AN - SCOPUS:84908086796
VL - 107
SP - 163
EP - 166
JO - Behavioural Processes
JF - Behavioural Processes
SN - 0376-6357
ER -