Contact dermatitis to a copper-containing intra-uterine device

This article describes a case in which a copper-containing IUD was associated with vaginitis and eczematous dermatitis in a 35-year-old woman. All lesions and symptoms subsided when the IUD was removed. Patch testing was positive to copper sulfate. The device had been inserted a few weeks prior to the onset of skin disease on the woman's trunk and limbs. It is possible that the metal is absorbed through the mucous membrane and carried to the skin via blood or via the committed T-lymphocytes. Since copper is widespread in the environment, its sensitizing potential is low and allergic reactions are rare.