A study was carried out on 50 workers in a floriculture centre to evaluate the incidence of contact dermatitis to Alstroemeria. 3 subjects gave positive reactions to aqueous and ethanolic extracts of cut flowers, stems and leaves. By column chromatography, the allergen was isolated and its chemical structure identified as 6-tuliposide A by proton magnetic resonance and carbon-13 magnetic resonance. Only 6-tuliposide A was isolated from cut flowers, and this gave positive reactions when patch tested at 0.01%; α-methylene-γ-butyrolactone at 10-5 (v/v) was positive in the same 3 subjects. Other lactones (γ-methylene-γ-butyrolactone, alantolactone, isoalantolactone) were negative at all concentrations used.
|Number of pages||5|
|Publication status||Published - 1985|
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