Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy: Clinical Genitourinary Cancer

E Mazzone; FA Mistretta; S Knipper; Z Tian; C Palumbo; G Gandaglia; D Soulieres; D Tilki; F Montorsi; SF Shariat; F Saad; A Briganti; PI Karakiewicz

doi:10.1016/j.clgc.2019.08.009

Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy: Clinical Genitourinary Cancer

E Mazzone, FA Mistretta, S Knipper, Z Tian, C Palumbo, G Gandaglia, D Soulieres, D Tilki, F Montorsi, SF Shariat, F Saad, A Briganti, PI Karakiewicz

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

In contemporary stage I nonseminoma germ-cell tumor of the testis (NSGCTT) patients, increasing use of surveillance and chemotherapy, in concordance with guideline recommendations, is evident. Long-term survival rates were comparable between surveillance and active treatment (AT) patients. Among AT, retroperitoneal lymph node dissection was associated with better long-term survival outcomes. These results confirm the contemporary adherence to guideline recommendations and also confirm the safety of surveillance in patients with stage I NSGCTT. © 2019 Elsevier Inc.

Original language	English
Pages (from-to)	e1153-e1162
Journal	Clinical Genitourinary Cancer
Volume	17
Issue number	6
DOIs	https://doi.org/10.1016/j.clgc.2019.08.009
Publication status	Published - 2019

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Mazzone, E., Mistretta, FA., Knipper, S., Tian, Z., Palumbo, C., Gandaglia, G., Soulieres, D., Tilki, D., Montorsi, F., Shariat, SF., Saad, F., Briganti, A., & Karakiewicz, PI. (2019). Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy: Clinical Genitourinary Cancer. Clinical Genitourinary Cancer, 17(6), e1153-e1162. https://doi.org/10.1016/j.clgc.2019.08.009

Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy : Clinical Genitourinary Cancer. / Mazzone, E; Mistretta, FA; Knipper, S; Tian, Z; Palumbo, C; Gandaglia, G; Soulieres, D; Tilki, D; Montorsi, F; Shariat, SF; Saad, F; Briganti, A; Karakiewicz, PI.

In: Clinical Genitourinary Cancer, Vol. 17, No. 6, 2019, p. e1153-e1162.

Research output: Contribution to journal › Article › peer-review

Mazzone, E, Mistretta, FA, Knipper, S, Tian, Z, Palumbo, C, Gandaglia, G, Soulieres, D, Tilki, D, Montorsi, F, Shariat, SF, Saad, F, Briganti, A & Karakiewicz, PI 2019, 'Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy: Clinical Genitourinary Cancer', Clinical Genitourinary Cancer, vol. 17, no. 6, pp. e1153-e1162. https://doi.org/10.1016/j.clgc.2019.08.009

Mazzone E, Mistretta FA, Knipper S, Tian Z, Palumbo C, Gandaglia G et al. Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy: Clinical Genitourinary Cancer. Clinical Genitourinary Cancer. 2019;17(6):e1153-e1162. https://doi.org/10.1016/j.clgc.2019.08.009

Mazzone, E ; Mistretta, FA ; Knipper, S ; Tian, Z ; Palumbo, C ; Gandaglia, G ; Soulieres, D ; Tilki, D ; Montorsi, F ; Shariat, SF ; Saad, F ; Briganti, A ; Karakiewicz, PI. / Contemporary Assessment of Long-Term Survival Rates in Patients With Stage I Nonseminoma Germ-Cell Tumor of the Testis: Population-Based Comparison Between Surveillance and Active Treatment After Initial Orchiectomy : Clinical Genitourinary Cancer. In: Clinical Genitourinary Cancer. 2019 ; Vol. 17, No. 6. pp. e1153-e1162.

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AB - In contemporary stage I nonseminoma germ-cell tumor of the testis (NSGCTT) patients, increasing use of surveillance and chemotherapy, in concordance with guideline recommendations, is evident. Long-term survival rates were comparable between surveillance and active treatment (AT) patients. Among AT, retroperitoneal lymph node dissection was associated with better long-term survival outcomes. These results confirm the contemporary adherence to guideline recommendations and also confirm the safety of surveillance in patients with stage I NSGCTT. © 2019 Elsevier Inc.

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