Abstract
Anarchic hand syndrome (AHS) is a rare neurological condition characterized by seemingly purposeful, goal-directed hand movements which the person afflicted by the syndrome is not, however, in control of. By extensively examining a patient with AHS we provide novel neuropsychological and lesion mapping data that shed new light on the possibility of modulating specific symptoms associated with AHS, in particular unilateral apraxia and magnetic apraxia. Moreover, we compared lesion mapping data with an in depth analysis of previous studies in order to explore the neural network responsible for the complex symptomatology associated with this syndrome. We found that non-primarily motor variables (e.g. the nature of the object to be grasped and integration of visuo-spatial feedback in action) play an important role in determining AHS symptomatology. Moreover, we found that lesions involving various different parts of the motor control network (the corpus callosum, the anterior cingulate cortex and the supplementary motor area, the parietal areas and thalamus) are closely linked to partially differing AHS symptoms. The comparison of our data with those reported in previous studies indicate that AHS is a multifaceted and complex syndrome in which the influence of non-primarily motor, emotional and higher-order components may be largely underestimated.
| Original language | English |
|---|---|
| Pages (from-to) | 122-129 |
| Number of pages | 8 |
| Journal | Neuropsychologia |
| Volume | 78 |
| DOIs | |
| Publication status | Published - Nov 1 2015 |
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Keywords
- Anarchic hand syndrome
- Dangerous stimulus
- Magnetic apraxia
- Unilateral apraxia
- Visual observation perspective
ASJC Scopus subject areas
- Behavioral Neuroscience
- Cognitive Neuroscience
- Experimental and Cognitive Psychology
Cite this
Contextual bottom-up and implicit top-down modulation of anarchic hand syndrome : A single-case report and a review of the literature. / Moro, Valentina; Pernigo, Simone; Scandola, Michele; Mainente, Maria; Avesani, Renato; Aglioti, Salvatore Maria.
In: Neuropsychologia, Vol. 78, 01.11.2015, p. 122-129.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Contextual bottom-up and implicit top-down modulation of anarchic hand syndrome
T2 - A single-case report and a review of the literature
AU - Moro, Valentina
AU - Pernigo, Simone
AU - Scandola, Michele
AU - Mainente, Maria
AU - Avesani, Renato
AU - Aglioti, Salvatore Maria
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Anarchic hand syndrome (AHS) is a rare neurological condition characterized by seemingly purposeful, goal-directed hand movements which the person afflicted by the syndrome is not, however, in control of. By extensively examining a patient with AHS we provide novel neuropsychological and lesion mapping data that shed new light on the possibility of modulating specific symptoms associated with AHS, in particular unilateral apraxia and magnetic apraxia. Moreover, we compared lesion mapping data with an in depth analysis of previous studies in order to explore the neural network responsible for the complex symptomatology associated with this syndrome. We found that non-primarily motor variables (e.g. the nature of the object to be grasped and integration of visuo-spatial feedback in action) play an important role in determining AHS symptomatology. Moreover, we found that lesions involving various different parts of the motor control network (the corpus callosum, the anterior cingulate cortex and the supplementary motor area, the parietal areas and thalamus) are closely linked to partially differing AHS symptoms. The comparison of our data with those reported in previous studies indicate that AHS is a multifaceted and complex syndrome in which the influence of non-primarily motor, emotional and higher-order components may be largely underestimated.
AB - Anarchic hand syndrome (AHS) is a rare neurological condition characterized by seemingly purposeful, goal-directed hand movements which the person afflicted by the syndrome is not, however, in control of. By extensively examining a patient with AHS we provide novel neuropsychological and lesion mapping data that shed new light on the possibility of modulating specific symptoms associated with AHS, in particular unilateral apraxia and magnetic apraxia. Moreover, we compared lesion mapping data with an in depth analysis of previous studies in order to explore the neural network responsible for the complex symptomatology associated with this syndrome. We found that non-primarily motor variables (e.g. the nature of the object to be grasped and integration of visuo-spatial feedback in action) play an important role in determining AHS symptomatology. Moreover, we found that lesions involving various different parts of the motor control network (the corpus callosum, the anterior cingulate cortex and the supplementary motor area, the parietal areas and thalamus) are closely linked to partially differing AHS symptoms. The comparison of our data with those reported in previous studies indicate that AHS is a multifaceted and complex syndrome in which the influence of non-primarily motor, emotional and higher-order components may be largely underestimated.
KW - Anarchic hand syndrome
KW - Dangerous stimulus
KW - Magnetic apraxia
KW - Unilateral apraxia
KW - Visual observation perspective
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UR - http://www.scopus.com/inward/citedby.url?scp=84944075340&partnerID=8YFLogxK
U2 - 10.1016/j.neuropsychologia.2015.10.005
DO - 10.1016/j.neuropsychologia.2015.10.005
M3 - Article
VL - 78
SP - 122
EP - 129
JO - Neuropsychologia
JF - Neuropsychologia
SN - 0028-3932
ER -