Continence, potency and oncological outcomes after robotic-assisted radical prostatectomy: Early trifecta results of a high-volume surgeon

Vipul R. Patel, Rafael F. Coelho, Sanket Chauhan, Marcelo A. Orvieto, Kenneth J. Palmer, Bernardo Rocco, Anathakrishnan Sivaraman, Geoff Coughlin

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE • To evaluate early trifecta outcomes after robotic-assisted radical prostatectomy (RARP) performed by a high-volume surgeon. PATIENTS AND METHODS • We evaluated prospectively 1100 consecutive patients who underwent RARP performed by one surgeon. In all, 541 men were considered potent before RARP; of these 404 underwent bilateral full nerve sparing and were included in this analysis. • Baseline and postoperative urinary and sexual functions were assessed using self-administered validated questionnaires. • Postoperative continence was defined as the use of no pads; potency was defined as the ability to achieve and maintain satisfactory erections for sexual intercourse >50% of times, with or without the use of oral phosphodiesterase type 5 inhibitors; Biochemical recurrence (BCR) was defined as two consecutive PSA levels of >0.2 ngmL after RARP. • Results were compared between three age groups: Group 1, ≤55 years, Group 2, 56-65 years and Group 3, >65 years. RESULTS • The trifecta rates at 6 weeks, 3, 6, 12, and 18 months after RARP were 42.8%, 65.3%, 80.3%, 86% and 91%, respectively. • There were no statistically significant differences in the continence and BCR-free rates between the three age groups at all postoperative intervals analysed. • Nevertheless, younger men had higher potency rates and shorter time to recovery of sexual function when compared with older men at 6 weeks, 3, 6 and 12 months after RARP (P <0.01 at all time points). • Similarly, younger men also had a shorter time to achieving the trifecta and had higher trifecta rates at 6 weeks, 3 and 6 months after RARP compared with older men (P <0.01 at all time points). CONCLUSION • RARP offers excellent short-term trifecta outcomes when performed by an experienced surgeon. • Younger men had a shorter time to achieving the trifecta and higher overall trifecta rates when compared with older men at 6 weeks, 3 and 6 months after RARP.

Original languageEnglish
Pages (from-to)696-702
Number of pages7
JournalBJU International
Volume106
Issue number5
DOIs
Publication statusPublished - Sep 2010

Keywords

  • prognosis
  • prostate cancer
  • prostatectomy
  • robotic
  • treatment outcome

ASJC Scopus subject areas

  • Urology

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