Continuous antibiotic infusion for salvage therapy of partially implanted central venous catheter tunnel infections due to staphylococci

M. Giacchino, S. Bezzio, N. Chiapello, P. Saracco, F. Fagioli, I. Caviglia, C. Moroni, E. Castagnola

Research output: Contribution to journalArticlepeer-review

Abstract

Tunnel infection is an uncommon but serious complication observed in patients with partially implanted central venous catheters. International guidelines suggest that should include antibiotics and catheter removal. A success rate of only 5-20% was reported without catheter removal. We treated 13 episodes of tunnel Gram-positive bacterial infection occurring in pediatric patients with cancer or serious blood disorders with 24-hr intracatheter antibiotic continuous infusion. This approach led to a 69% success rate. Continuous infusion might be an attractive option to treat tunnel Gram-positive bacterial infections when catheter removal might not be feasible or advisable.

Original languageEnglish
Pages (from-to)1010-1012
Number of pages3
JournalPediatric Blood and Cancer
Volume49
Issue number7
DOIs
Publication statusPublished - Dec 2007

Keywords

  • Central venous catheter
  • Children
  • Therapy
  • Tunnel infection

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Pediatrics, Perinatology, and Child Health

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