Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure

Piergiuseppe Agostoni; Gianluca Caldara; Maurizio Bussotti; Miriam Revera; Mariaconsuelo Valentini; Francesca Gregorini; Andrea Faini; Carolina Lombardi; Gregorz Bilo; Andrea Giuliano; Fabrizio Veglia; Giulio Savia; Pietro A. Modesti; Giuseppe Mancia; Gianfranco Parati

doi:10.1093/eurheartj/ehp472

Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure

Piergiuseppe Agostoni, Gianluca Caldara, Maurizio Bussotti, Miriam Revera, Mariaconsuelo Valentini, Francesca Gregorini, Andrea Faini, Carolina Lombardi, Gregorz Bilo, Andrea Giuliano, Fabrizio Veglia, Giulio Savia, Pietro A. Modesti, Giuseppe Mancia, Gianfranco Parati

Research output: Contribution to journal › Article › peer-review

Abstract

AimsIt is unknown whether subclinical high-altitude pulmonary oedema reduces spontaneously after prolonged altitude exposure. Continuous positive airway pressure (CPAP) removes extravascular lung fluids and improves haemoglobin oxygen saturation in acute cardiogenic oedema. We evaluated the presence of pulmonary extravascular fluid increase by assessing CPAP effects on haemoglobin oxygen saturation under acute and prolonged altitude exposure.Methods and resultsWe applied 7 cm H₂O CPAP for 30 min to healthy individuals after acute (Capanna Margherita, CM, 4559 m, 2 days permanence, and 2-sat increase suggesting a reduction in alveolar fluids.

Original language	English
Pages (from-to)	457-463
Number of pages	7
Journal	European Heart Journal
Volume	31
Issue number	4
DOIs	https://doi.org/10.1093/eurheartj/ehp472
Publication status	Published - Feb 2010

Keywords

Arterial blood oxygen saturation
High altitude pulmonary oedema
Hypobaric hypoxia at altitude
Positive pressure ventilation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1093/eurheartj/ehp472

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Agostoni, P., Caldara, G., Bussotti, M., Revera, M., Valentini, M., Gregorini, F., Faini, A., Lombardi, C., Bilo, G., Giuliano, A., Veglia, F., Savia, G., Modesti, P. A., Mancia, G., & Parati, G. (2010). Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure. European Heart Journal, 31(4), 457-463. https://doi.org/10.1093/eurheartj/ehp472

Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure. / Agostoni, Piergiuseppe; Caldara, Gianluca; Bussotti, Maurizio; Revera, Miriam; Valentini, Mariaconsuelo; Gregorini, Francesca; Faini, Andrea ; Lombardi, Carolina ; Bilo, Gregorz; Giuliano, Andrea; Veglia, Fabrizio; Savia, Giulio; Modesti, Pietro A.; Mancia, Giuseppe; Parati, Gianfranco.

In: European Heart Journal, Vol. 31, No. 4, 02.2010, p. 457-463.

Research output: Contribution to journal › Article › peer-review

Agostoni, P, Caldara, G, Bussotti, M, Revera, M, Valentini, M, Gregorini, F, Faini, A , Lombardi, C , Bilo, G, Giuliano, A, Veglia, F, Savia, G, Modesti, PA, Mancia, G & Parati, G 2010, 'Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure', European Heart Journal, vol. 31, no. 4, pp. 457-463. https://doi.org/10.1093/eurheartj/ehp472

Agostoni, Piergiuseppe ; Caldara, Gianluca ; Bussotti, Maurizio ; Revera, Miriam ; Valentini, Mariaconsuelo ; Gregorini, Francesca ; Faini, Andrea ; Lombardi, Carolina ; Bilo, Gregorz ; Giuliano, Andrea ; Veglia, Fabrizio ; Savia, Giulio ; Modesti, Pietro A. ; Mancia, Giuseppe ; Parati, Gianfranco. / Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure. In: European Heart Journal. 2010 ; Vol. 31, No. 4. pp. 457-463.

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abstract = "AimsIt is unknown whether subclinical high-altitude pulmonary oedema reduces spontaneously after prolonged altitude exposure. Continuous positive airway pressure (CPAP) removes extravascular lung fluids and improves haemoglobin oxygen saturation in acute cardiogenic oedema. We evaluated the presence of pulmonary extravascular fluid increase by assessing CPAP effects on haemoglobin oxygen saturation under acute and prolonged altitude exposure.Methods and resultsWe applied 7 cm H2O CPAP for 30 min to healthy individuals after acute (Capanna Margherita, CM, 4559 m, 2 days permanence, and 2-sat increase suggesting a reduction in alveolar fluids.",

keywords = "Arterial blood oxygen saturation, High altitude pulmonary oedema, Hypobaric hypoxia at altitude, Positive pressure ventilation",

author = "Piergiuseppe Agostoni and Gianluca Caldara and Maurizio Bussotti and Miriam Revera and Mariaconsuelo Valentini and Francesca Gregorini and Andrea Faini and Carolina Lombardi and Gregorz Bilo and Andrea Giuliano and Fabrizio Veglia and Giulio Savia and Modesti, {Pietro A.} and Giuseppe Mancia and Gianfranco Parati",

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AU - Agostoni, Piergiuseppe

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AU - Bussotti, Maurizio

AU - Revera, Miriam

AU - Valentini, Mariaconsuelo

AU - Gregorini, Francesca

AU - Faini, Andrea

AU - Lombardi, Carolina

AU - Bilo, Gregorz

AU - Giuliano, Andrea

AU - Veglia, Fabrizio

AU - Savia, Giulio

AU - Modesti, Pietro A.

AU - Mancia, Giuseppe

AU - Parati, Gianfranco

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AB - AimsIt is unknown whether subclinical high-altitude pulmonary oedema reduces spontaneously after prolonged altitude exposure. Continuous positive airway pressure (CPAP) removes extravascular lung fluids and improves haemoglobin oxygen saturation in acute cardiogenic oedema. We evaluated the presence of pulmonary extravascular fluid increase by assessing CPAP effects on haemoglobin oxygen saturation under acute and prolonged altitude exposure.Methods and resultsWe applied 7 cm H2O CPAP for 30 min to healthy individuals after acute (Capanna Margherita, CM, 4559 m, 2 days permanence, and 2-sat increase suggesting a reduction in alveolar fluids.

KW - Arterial blood oxygen saturation

KW - High altitude pulmonary oedema

KW - Hypobaric hypoxia at altitude

KW - Positive pressure ventilation

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