Continuous subcutaneous insulin infusion in children and adolescents with diabetes mellitus: Decreased HbA1c with low risk of hypoglycemia

Nicoletta Sulli, B. Shashaj

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To evaluate blood glucose and HbA1c levels, insulin dosage, hypoglycemia rate and body mass index (BMI) at baseline, and at 3 and 6 months after initiation of continuous subcutaneous insulin infusion (CSII) in children and youth with type 1 diabetes mellitus (DM). Methods: A 6-month trial of pump therapy was carried out in 40 patients with type 1 DM and one with cystic fibrosis (CF) induced DM (25 males), aged 4-25 years (mean 13.5 ± 4.2 [SD]; 4-8 years, n = 6; 8-10 years, n = 8; 10-12 years, n = 4; 12-15 years, n = 11; >15 years, n = 12). Results: HbA1c was significantly reduced from 9.5 ± 1.7% to 8.6 ± 1.2% at 3 months (p

Original languageEnglish
Pages (from-to)393-399
Number of pages7
JournalJournal of Pediatric Endocrinology and Metabolism
Volume16
Issue number3
Publication statusPublished - 2003

Keywords

  • CSII
  • Diabetic children
  • Insulin pump therapy
  • Intensified treatment
  • Type 1 diabetes mellitus

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health

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