Contrast-Enhanced Sonography of the Spleen

Orlando Catalano, Fabio Sandomenico, Paolo Vallone, Adolfo Gallipoli d'Errico, Alfredo Siani

Research output: Contribution to journalArticlepeer-review


Sonography is frequently the first imaging modality employed to evaluate the spleen. Nevertheless, splenic abnormalities frequently determine subtle changes in echogenicity and may be overlooked. Additionally, splenic disorders have a nonspecific appearance, mostly appearing as hypoechoic defects. Difficulties in differential diagnosis are not uncommon, with splenic infarctions resembling, for example, focal lesions. Color Doppler is usually of limited additional value. Instead, the spleen is optimally suited for contrast-enhanced sonography, being superficial, small, and homogeneous, and showing intense and persistent contrast enhancement. Scarcely evident abnormalities become evident after contrast medium injection. Additional information can be obtained in many clinical scenarios, including blunt trauma, left flank pain, lymphoma, and incidental detection of splenic abnormalities.

Original languageEnglish
Pages (from-to)426-433
Number of pages8
JournalSeminars in Ultrasound, CT and MRI
Issue number5
Publication statusPublished - Oct 2006

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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