Ecografia con mezzo di contrasto (CEUS) immediatamente dopo ablazione percutanea dell'epatocarcinoma

Translated title of the contribution: Contrast-enhanced ultrasonography (CEUS) immediately after percutaneous ablation of hepatocellular carcinoma

A. Gallotti, M. D'Onofrio, A. Ruzzenente, E. Martone, R. De Robertis, A. Guglielmi, R. Pozzi Mucelli

Research output: Contribution to journalArticle

Abstract

Purpose: This study evaluated the effectiveness of contrast-enhanced ultrasound (CEUS), performed immediately after percutaneous ethanol injection (PEI) or radiofrequency thermal ablation (RFTA), by comparing results with the computed tomography (CT) follow-up. Materials and methods: Sixty-nine consecutive patients with a diagnosis of hepatocellular carcinoma (HCC) were included in this prospective study. All patients underwent PEI or RFTA. After treatment, three CEUS enhancement patterns were observed: isovascular, hypovascular and avascular, which were compared with the CT findings. Sensitivity of the avascular pattern at CEUS and effectiveness of the ablative procedures were evaluated and compared with the chi-square test. Results: Ninety hypervascular HCCs, with a mean diameter of 2.6 cm (0.5-4.9 cm), underwent PEI (n=54) and RFTA (n=36). In the first group, CT identified complete necrosis in 28/54 (52%) lesions, 21 (75%) of which had avascular, one (4%) isovascular and six (21%) hypovascular patterns at CEUS. In the second group, CT showed complete necrosis in 31/36 (86%) lesions, all (100%) of which had a corresponding avascular pattern at CEUS. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the avascular pattern at CEUS compared with CT findings were 75%, 69%, 72%, 72% and 72% for PEI and 100%, 20%, 89%, 100% and 89%, for RFTA, respectively. A statistically significant difference (p

Original languageItalian
Pages (from-to)1094-1105
Number of pages12
JournalRadiologia Medica
Volume114
Issue number7
DOIs
Publication statusPublished - Oct 2009

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Hepatocellular Carcinoma
Ultrasonography
Tomography
Ethanol
Hot Temperature
Injections
Necrosis
Chi-Square Distribution
Prospective Studies
Sensitivity and Specificity
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Gallotti, A., D'Onofrio, M., Ruzzenente, A., Martone, E., De Robertis, R., Guglielmi, A., & Pozzi Mucelli, R. (2009). Ecografia con mezzo di contrasto (CEUS) immediatamente dopo ablazione percutanea dell'epatocarcinoma. Radiologia Medica, 114(7), 1094-1105. https://doi.org/10.1007/s11547-009-0436-0

Ecografia con mezzo di contrasto (CEUS) immediatamente dopo ablazione percutanea dell'epatocarcinoma. / Gallotti, A.; D'Onofrio, M.; Ruzzenente, A.; Martone, E.; De Robertis, R.; Guglielmi, A.; Pozzi Mucelli, R.

In: Radiologia Medica, Vol. 114, No. 7, 10.2009, p. 1094-1105.

Research output: Contribution to journalArticle

Gallotti, A, D'Onofrio, M, Ruzzenente, A, Martone, E, De Robertis, R, Guglielmi, A & Pozzi Mucelli, R 2009, 'Ecografia con mezzo di contrasto (CEUS) immediatamente dopo ablazione percutanea dell'epatocarcinoma', Radiologia Medica, vol. 114, no. 7, pp. 1094-1105. https://doi.org/10.1007/s11547-009-0436-0
Gallotti, A. ; D'Onofrio, M. ; Ruzzenente, A. ; Martone, E. ; De Robertis, R. ; Guglielmi, A. ; Pozzi Mucelli, R. / Ecografia con mezzo di contrasto (CEUS) immediatamente dopo ablazione percutanea dell'epatocarcinoma. In: Radiologia Medica. 2009 ; Vol. 114, No. 7. pp. 1094-1105.
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AU - De Robertis, R.

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