Contribution of electron microscopy to study in vitro inositol effects on human spermatozoa

Research output: Contribution to journalArticle

Abstract

Infertility is a worldwide problem and male partner contributes to almost 30% of cases of infertility. The term oligoasthenoteratospermia is related to defective spermatogenesis and is characterized by a reduction of motility and number of spermatozoa and a change in their morphology. Electron microscopes are frequently used in order to evaluate sperm pathology and overall to establish a correlation between structural and functional deficiencies of altered sperm. High levels of reactive oxygen species endanger sperm function and viability. The correlation between male infertility, reactive oxygen species levels and the innovative therapeutic strategy employing inositol has been highlighted through analysis of literature data.

Original languageEnglish
Pages (from-to)4-9
Number of pages6
JournalEuropean Review for Medical and Pharmacological Sciences
Volume21
Issue number2 Suppl
Publication statusPublished - Jun 2017

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Inositol
Spermatozoa
Electron Microscopy
Infertility
Reactive Oxygen Species
Male Infertility
Spermatogenesis
Electrons
Pathology
In Vitro Techniques
Therapeutics

Cite this

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title = "Contribution of electron microscopy to study in vitro inositol effects on human spermatozoa",
abstract = "Infertility is a worldwide problem and male partner contributes to almost 30{\%} of cases of infertility. The term oligoasthenoteratospermia is related to defective spermatogenesis and is characterized by a reduction of motility and number of spermatozoa and a change in their morphology. Electron microscopes are frequently used in order to evaluate sperm pathology and overall to establish a correlation between structural and functional deficiencies of altered sperm. High levels of reactive oxygen species endanger sperm function and viability. The correlation between male infertility, reactive oxygen species levels and the innovative therapeutic strategy employing inositol has been highlighted through analysis of literature data.",
author = "M Colone and A Calcabrini and V Unfer and A Stringaro",
year = "2017",
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AU - Calcabrini, A

AU - Unfer, V

AU - Stringaro, A

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N2 - Infertility is a worldwide problem and male partner contributes to almost 30% of cases of infertility. The term oligoasthenoteratospermia is related to defective spermatogenesis and is characterized by a reduction of motility and number of spermatozoa and a change in their morphology. Electron microscopes are frequently used in order to evaluate sperm pathology and overall to establish a correlation between structural and functional deficiencies of altered sperm. High levels of reactive oxygen species endanger sperm function and viability. The correlation between male infertility, reactive oxygen species levels and the innovative therapeutic strategy employing inositol has been highlighted through analysis of literature data.

AB - Infertility is a worldwide problem and male partner contributes to almost 30% of cases of infertility. The term oligoasthenoteratospermia is related to defective spermatogenesis and is characterized by a reduction of motility and number of spermatozoa and a change in their morphology. Electron microscopes are frequently used in order to evaluate sperm pathology and overall to establish a correlation between structural and functional deficiencies of altered sperm. High levels of reactive oxygen species endanger sperm function and viability. The correlation between male infertility, reactive oxygen species levels and the innovative therapeutic strategy employing inositol has been highlighted through analysis of literature data.

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JO - European Review for Medical and Pharmacological Sciences

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