Contribution of endothelial precursors of adipose tissue to breast cancer: Progression-link with fat graft for reconstructive surgery

Research output: Contribution to journalArticle

Abstract

Obesity, an excess accumulation of adipose tissue occurring in mammalians when caloric intake exceeds energy expenditure, is associated with an increased frequency and progression of several types of neoplastic diseases including postmenopausal breast cancer. Recent studies have suggested that obesity-related disruption of the energy homeostasis results in inflammation and alterations of adipokine signalling that may foster cancer initiation and progression. Moreover, two populations of human white adipose tissue (WAT) progenitors cooperate in breast cancer angiogenesis, growth and metastatic progression. This raises the issue of lipotransfer in patients undergoing plastic or reconstructive surgery.

Original languageEnglish
Pages (from-to)106-107
Number of pages2
JournalAnnales d'Endocrinologie
Volume74
Issue number2
DOIs
Publication statusPublished - May 2013

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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