Background-We used intravascular ultrasound (IVUS) to evaluate recurrence after sirolimus-eluting stent (SES) implantation treatment of in-stent restenosis (ISR). Methods and Results-Forty-eight ISR lesions (41 patients with objective evidence of ischemia) were treated with SES. Recurrent ISR was identified in 11 lesions (all focal); repeat revascularization was performed in 10. These were compared with 16 patients (19 lesions) without recurrence as documented by angiography. Nine of 11 recurrent lesions had a minimum stent area (MSA) 2 versus 5 of 19 nonrecurrent lesions (P=0.003) ; 7 of 11 recurrent lesions had an MSA 2 versus 4 of 19 nonrecurrent lesions (P=0.02); and 4 of 11 recurrent lesions had an MSA 2 versus 1 of 19 nonrecurrent lesions (P=0.03). A gap between SESs was identified in 3 of 11 recurrences versus 1 of 19 nonrecurrent lesions. Conclusions-Stent underexpansion is a significant cause of failure after SES implantation treatment of ISR.
|Number of pages||4|
|Publication status||Published - Mar 9 2004|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine