Control of antibiotic therapy in pediatric patients. I. A computer system to collect and analyze antibiotic prescriptions in hospitals

N. Principi, D. Sher, R. C. Moresco, P. Marchisio, A. Boccazzi, G. Viola, F. Sereni

Research output: Contribution to journalArticlepeer-review

Abstract

A computer system to record and analyze antibiotic prescriptions in hospitalized children is described. This system is especially organized in order to obtain simultaneously a quantitative evaluation of antibiotic use and a qualitative analysis of the process by which the physician makes his decision for therapy. The practical employment of this program has been demonstrated by analyzing 765 prescriptions given in 9 different pediatric hospital wards. Many errors of prescription have been demonstrated: antibiotic therapy was based on the clinical impression alone in 31.5% of the prescriptions, antibiotic choice was rational in 20.1% and the posology prescribed complied with the usually applied schemes in 22.4%. Finally, the physician's attitude regarding laboratory monitoring of side-effects was adequate in 52.8% before treatment and 33.4% during antibiotic treatment.

Original languageEnglish
Pages (from-to)145-155
Number of pages11
JournalDevelopmental Pharmacology and Therapeutics
Volume2
Issue number3
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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