Control of breathing using an extracorporeal membrane lung

T. Kolobow, L. Gattinoni, T. A J E Tomlinson and Pierce

Research output: Contribution to journalArticlepeer-review


Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung. When extracorporeal CO2 removal approximated CO2 production (V(co2)), alveolar ventilation almost ceased. Pulmonary ventilation can be controlled by extracorporeal carbon dioxide removal.

Original languageEnglish
Pages (from-to)138-141
Number of pages4
Issue number2
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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