Control of ColE1 plasmid replication by antisense RNA

G. Cesareni, M. Helmer-Citterich, L. Castagnoli

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

One of the two major classes of regulatory strategies that control plasmid copy number involves recognition via base pairing between two plasmid-encoded complementary RNAs. The detailed analysis of this control circuitry has revealed some features of regulatory mechanisms based on RNA-RNA interaction that distinguish then from those based on protein-nucleic acid interaction. These features provide a framework with which to understand other regulatory mechanisms based on RNA-RNA interaction, and will aid in the design of efficient artificial antisense RNA systems.

Original languageEnglish
Pages (from-to)230-235
Number of pages6
JournalTrends in Genetics
Volume7
Issue number7
DOIs
Publication statusPublished - 1991

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Antisense RNA
Plasmids
RNA
Complementary RNA
Base Pairing
Nucleic Acids
Proteins

ASJC Scopus subject areas

  • Genetics

Cite this

Cesareni, G., Helmer-Citterich, M., & Castagnoli, L. (1991). Control of ColE1 plasmid replication by antisense RNA. Trends in Genetics, 7(7), 230-235. https://doi.org/10.1016/0168-9525(91)90370-6

Control of ColE1 plasmid replication by antisense RNA. / Cesareni, G.; Helmer-Citterich, M.; Castagnoli, L.

In: Trends in Genetics, Vol. 7, No. 7, 1991, p. 230-235.

Research output: Contribution to journalArticle

Cesareni, G, Helmer-Citterich, M & Castagnoli, L 1991, 'Control of ColE1 plasmid replication by antisense RNA', Trends in Genetics, vol. 7, no. 7, pp. 230-235. https://doi.org/10.1016/0168-9525(91)90370-6
Cesareni, G. ; Helmer-Citterich, M. ; Castagnoli, L. / Control of ColE1 plasmid replication by antisense RNA. In: Trends in Genetics. 1991 ; Vol. 7, No. 7. pp. 230-235.
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