Controllo degli effetti collaterali della ketamina: clordemetildiazepam vs diazepam in preanestesia.

Translated title of the contribution: Control of the side effects of ketamine: chlordemethyldiazepam vs diazepam in pre-anesthesia

C. D'Eramo, N. Stocchetti, W. Iacovelli, A. Salvadori

Research output: Contribution to journalArticle

Abstract

The pre-operative circulatory and psychotomimetic side-effects are studied in one hundred patients undergoing elective plastic-reconstructive surgery and anesthetized by ketamine 5-8 mg/kg i.m. Fifty patients were premedicated by atropine 0.01 mg/kg + CDDz 0.0285 mg/kg i.m. (group C), fifty by atropine 0.01 mg/kg + Dz 0.14 mg/kg i.m. (group D). All patients breathed spontaneously. Statistical analysis was performed with X 2 test. Not statistical difference was observed for the circulatory side-effects, whereas the frequency of emergence phenomena fell significantly from 31% to 14% (p less than 0.05) with CDDZ in greater than 16 years old patients. These finding seem confirm that CDDZ is more effective than DZ in reducing the psychotomimetic side-effects of ketamine, though it may be recommended a its wider experiment in this connection.

Translated title of the contributionControl of the side effects of ketamine: chlordemethyldiazepam vs diazepam in pre-anesthesia
Original languageItalian
Pages (from-to)413-417
Number of pages5
JournalMinerva Anestesiologica
Volume55
Issue number10
Publication statusPublished - Oct 1989

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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