Controversies in the therapy of low-grade glioma

When and how to treat

Alba A. Brandes, Francesca Vastola, Umberto Basso

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Treatment of low-grade gliomas is one of the most challenging management dilemmas in neuro-oncology. Young age of onset and low rate of growth theoretically favor minimally Invasive treatments. Yet, local recurrence and conversion to malignant glioma are the expected outcome within 4-8 years from diagnosis and impose the use of additional therapies, such as radiotherapy and chemotherapy. Due to low Incidence and paucity of randomized trials, the correct timing and dosage of radiotherapy are still controversial, as well as the indications and possible benefits of the administration of cytotoxic drugs. Current concepts and future perspectives in the treatment of low-grade gliomas drawn from recent scientific literature are here summarized and discussed.

Original languageEnglish
Pages (from-to)529-536
Number of pages8
JournalExpert Review of Anticancer Therapy
Volume2
Issue number5
Publication statusPublished - Oct 2002

Fingerprint

Glioma
Radiotherapy Dosage
Literature
Therapeutics
Age of Onset
Radiotherapy
Recurrence
Drug Therapy
Incidence
Growth
Pharmaceutical Preparations

Keywords

  • Chemotherapy
  • Low-grade gliomas
  • Radiotherapy
  • Review
  • Surgery

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

Cite this

Controversies in the therapy of low-grade glioma : When and how to treat. / Brandes, Alba A.; Vastola, Francesca; Basso, Umberto.

In: Expert Review of Anticancer Therapy, Vol. 2, No. 5, 10.2002, p. 529-536.

Research output: Contribution to journalArticle

Brandes, Alba A. ; Vastola, Francesca ; Basso, Umberto. / Controversies in the therapy of low-grade glioma : When and how to treat. In: Expert Review of Anticancer Therapy. 2002 ; Vol. 2, No. 5. pp. 529-536.
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