Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study

Lauren M. McGrath, Dongmei Yu, Christian Marshall, Lea K. Davis, Bhooma Thiruvahindrapuram, Bingbin Li, Carolina Cappi, Gloria Gerber, Aaron Wolf, Frederick A. Schroeder, Lisa Osiecki, Colm O'Dushlaine, Andrew Kirby, Cornelia Illmann, Stephen Haddad, Patience Gallagher, Jesen A. Fagerness, Cathy L. Barr, Laura Bellodi, Fortu BenarrochO. Joseph Bienvenu, Donald W. Black, Michael H. Bloch, Ruth D. Bruun, Cathy L. Budman, Beatriz Camarena, Danielle C. Cath, Maria C. Cavallini, Sylvain Chouinard, Vladimir Coric, Bernadette Cullen, Richard Delorme, Damiaan Denys, Eske M. Derks, Yves Dion, Maria C. Rosário, Valsama Eapen, Patrick Evans, Peter Falkai, Thomas V. Fernandez, Helena Garrido, Daniel Geller, Hans J. Grabe, Marco A. Grados, Benjamin D. Greenberg, Varda Gross-Tsur, Edna Grünblatt, Gary A. Heiman, Sian M J Hemmings, Luis D. Herrera, Ana G. Hounie, Joseph Jankovic, James L. Kennedy, Robert A. King, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F. Leckman, Leonhard Lennertz, Christine Lochner, Thomas L. Lowe, Gholson J. Lyon, Fabio MacCiardi, Wolfgang Maier, James T. McCracken, William McMahon, Dennis L. Murphy, Allan L. Naarden, Benjamin M. Neale, Erika Nurmi, Andrew J. Pakstis, Michele T. Pato, Carlos N. Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Victor I. Reus, Margaret A. Richter, Mark Riddle, Mary M. Robertson, David Rosenberg, Guy A. Rouleau, Stephan Ruhrmann, Aline S. Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S. Singer, Jan H. Smit, Dan J. Stein, Jay A. Tischfield, Homero Vallada, Jeremy Veenstra-Vanderweele, Susanne Walitza, Ying Wang, Jens R. Wendland, Yin Yao Shugart, Euripedes C. Miguel, Humberto Nicolini, Ben A. Oostra, Rainald Moessner, Michael Wagner, Andres Ruiz-Linares, Peter Heutink, Gerald Nestadt, Nelson Freimer, Tracey Petryshen, Danielle Posthuma, Michael A. Jenike, Nancy J. Cox, Gregory L. Hanna, Helena Brentani, Stephen W. Scherer, Paul D. Arnold, S. Evelyn Stewart, Carol A. Mathews, James A. Knowles, Edwin H. Cook, David L. Pauls, Kai Wang, Jeremiah M. Scharf

Research output: Contribution to journalArticlepeer-review

Abstract

Objective Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology. This study represents the first genome-wide investigation of large (>500 kb), rare (

Original languageEnglish
Pages (from-to)910-919
Number of pages10
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume53
Issue number8
DOIs
Publication statusPublished - 2014

Keywords

  • 16p13.11
  • copy number variation
  • genetics
  • obsessive-compulsive disorder
  • Tourette syndrome

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

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