TY - JOUR
T1 - CoreValve implantation for severe aortic regurgitation
T2 - a multicentre registry
AU - Testa, Luca
AU - Latib, Azeem
AU - Rossi, Marco L uciano
AU - De Marco, Federico
AU - De Carlo, Marco
AU - Fiorina, Claudia
AU - Oreglia, Jacopo
AU - Petronio, Anna S onia
AU - Ettori, Federica
AU - De Servi, Stefano
AU - Klugmann, Silvio
AU - Ussia, Gian P aolo
AU - Tamburino, Corrado
AU - Panisi, Paolo
AU - Brambilla, Nedy
AU - Colombo, Antonio
AU - Presbitero, Patrizia
AU - Bedogni, Francesco
PY - 2014/10/1
Y1 - 2014/10/1
N2 - AIMS: We sought to evaluate the outcome of transcatheter aortic valve replacement (TAVR) with the CoreValve Revalving System (CRS-TAVR) in inoperable patients presenting with severe aortic regurgitation (AR), compared to in patients treated for severe native aortic stenosis (AS). From October 2008 to January 2013, 1,557 consecutive patients undergoing CRS-TAVR, of whom 26 (1.6%) presented with AR, were prospectively followed. Compared with patients with AS, patients with AR were significantly younger (mean age 73±10 vs. 82±6, p=0.02), more frequently in NYHA Class III/IV (95% vs. 73%, p=0.01) and had a higher incidence of severe pulmonary hypertension (sPAP >60 mmHg, 31% vs. 10%, p=0.007). Log EuroSCORE and STS score were similar. VARC-2-defined device success was lower in the AR group (79% vs. 96%, p=0.006). At one month, patients treated for AR had a higher overall mortality (23% vs. 5.9%; OR 4.22 [3.03-8.28], p
AB - AIMS: We sought to evaluate the outcome of transcatheter aortic valve replacement (TAVR) with the CoreValve Revalving System (CRS-TAVR) in inoperable patients presenting with severe aortic regurgitation (AR), compared to in patients treated for severe native aortic stenosis (AS). From October 2008 to January 2013, 1,557 consecutive patients undergoing CRS-TAVR, of whom 26 (1.6%) presented with AR, were prospectively followed. Compared with patients with AS, patients with AR were significantly younger (mean age 73±10 vs. 82±6, p=0.02), more frequently in NYHA Class III/IV (95% vs. 73%, p=0.01) and had a higher incidence of severe pulmonary hypertension (sPAP >60 mmHg, 31% vs. 10%, p=0.007). Log EuroSCORE and STS score were similar. VARC-2-defined device success was lower in the AR group (79% vs. 96%, p=0.006). At one month, patients treated for AR had a higher overall mortality (23% vs. 5.9%; OR 4.22 [3.03-8.28], p
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U2 - 10.4244/EIJV10I6A127
DO - 10.4244/EIJV10I6A127
M3 - Article
C2 - 25330506
AN - SCOPUS:84936758191
VL - 10
SP - 739
EP - 745
JO - EuroIntervention
JF - EuroIntervention
SN - 1774-024X
IS - 6
ER -