Coriander (Coriandrum sativum) Essential Oil

Effect on Multidrug Resistant Uropathogenic Escherichia coli

Francesca Scazzocchio, Lorenzo Mondì, Maria Grazia Ammendolia, Paola Goldoni, Antonella Comanducci, Massimiliano Marazzato, Maria Pia Conte, Federica Rinaldi, Maria Elisa Crestoni, Caterina Fraschetti, Catia Longhi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Coriander (Coriandrum sativum L., Apiaceae) is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil (CDO) against multidrug resistant uropathogenic Escherichia coli (UPEC). CDO was able to inhibit the growth of UPEC strains and propidium iodide uptake, and electron microscopy examination suggested that bacterial structural modifications occurred. The presence of CDO reduced the MIC of gentamicin. E.coli adhesion efficiency on cell monolayers and abiotic surfaces was not affected by subMIC oil concentrations; furthermore, CDO showed cytotoxic activity towards the HEp-2 tumor cell line. These findings contribute to the knowledge about essential oils as sources of potential antimicrobial agents against uropathogenic E. coli and encourage further investigations.

Original languageEnglish
Pages (from-to)623-626
Number of pages4
JournalNatural Product Communications
Volume12
Issue number4
Publication statusPublished - Jan 1 2017

Fingerprint

uropathogenic Escherichia coli
Coriandrum
Uropathogenic Escherichia coli
Coriandrum sativum
Volatile Oils
essential oils
anti-infective agents
Apiaceae
Propidium
gentamicin
Anti-Infective Agents
Gentamicins
Tumor Cell Line
adhesion
electron microscopy
Electron Microscopy
Oils
cell lines
Escherichia coli
oils

Keywords

  • Antibiotic resistance
  • Coriandrum sativum
  • Escherichia coli
  • Essential oil
  • Urinary tract infections
  • Uropathogenic Escherichia coli

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

Cite this

Scazzocchio, F., Mondì, L., Ammendolia, M. G., Goldoni, P., Comanducci, A., Marazzato, M., ... Longhi, C. (2017). Coriander (Coriandrum sativum) Essential Oil: Effect on Multidrug Resistant Uropathogenic Escherichia coli. Natural Product Communications, 12(4), 623-626.

Coriander (Coriandrum sativum) Essential Oil : Effect on Multidrug Resistant Uropathogenic Escherichia coli. / Scazzocchio, Francesca; Mondì, Lorenzo; Ammendolia, Maria Grazia; Goldoni, Paola; Comanducci, Antonella; Marazzato, Massimiliano; Conte, Maria Pia; Rinaldi, Federica; Crestoni, Maria Elisa; Fraschetti, Caterina; Longhi, Catia.

In: Natural Product Communications, Vol. 12, No. 4, 01.01.2017, p. 623-626.

Research output: Contribution to journalArticle

Scazzocchio, F, Mondì, L, Ammendolia, MG, Goldoni, P, Comanducci, A, Marazzato, M, Conte, MP, Rinaldi, F, Crestoni, ME, Fraschetti, C & Longhi, C 2017, 'Coriander (Coriandrum sativum) Essential Oil: Effect on Multidrug Resistant Uropathogenic Escherichia coli', Natural Product Communications, vol. 12, no. 4, pp. 623-626.
Scazzocchio, Francesca ; Mondì, Lorenzo ; Ammendolia, Maria Grazia ; Goldoni, Paola ; Comanducci, Antonella ; Marazzato, Massimiliano ; Conte, Maria Pia ; Rinaldi, Federica ; Crestoni, Maria Elisa ; Fraschetti, Caterina ; Longhi, Catia. / Coriander (Coriandrum sativum) Essential Oil : Effect on Multidrug Resistant Uropathogenic Escherichia coli. In: Natural Product Communications. 2017 ; Vol. 12, No. 4. pp. 623-626.
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