Corneal curvature and thickness development in premature infants

Silvana de Silva, Fulvio Parentin, Paola Michieletto, Stefano Pensiero

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: Analysis of postnatal changes in central corneal thickness (CCT) and corneal curvature (CC) in premature infants, their relation, and their possible influence on eye growth and intraocular pressure (IOP) evaluation. Methods: CCT and CC were assessed in both eyes of 56 premature infants, born at 24 to 32 weeks of gestational age (GA), and then two or three times at post-conceptional ages (PCAs) of 28 to 42 weeks. Results: CC changed from 65.83 diopters at 28 weeks of PCA to 49.38 diopters at 42 weeks of PCA. CCT decreased from 794 to 559 μm at the same ages. The reductions of these two corneal parameters seem to be related to each other and begin immediately after birth. Conclusion: In light of the few data available in the literature, these data provide more certainty about the CCT values of premature infants. The importance of CCT and CC fast variations after premature birth concerns both the knowledge of anterior segment development and the correct evaluation of IOP in immature eyes; the influence of these two parameters on the methods of IOP evaluation could be more remarkable at the lowest PCAs.

Original languageEnglish
Pages (from-to)25-29
Number of pages5
JournalJournal of Pediatric Ophthalmology and Strabismus
Volume48
Issue number1
DOIs
Publication statusPublished - Jan 2011

Fingerprint

Intraocular Pressure
Premature Infants
Premature Birth
Gestational Age
Parturition
Growth

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Corneal curvature and thickness development in premature infants. / de Silva, Silvana; Parentin, Fulvio; Michieletto, Paola; Pensiero, Stefano.

In: Journal of Pediatric Ophthalmology and Strabismus, Vol. 48, No. 1, 01.2011, p. 25-29.

Research output: Contribution to journalArticle

@article{f433791ec3a9466da4bde2ec64245b50,
title = "Corneal curvature and thickness development in premature infants",
abstract = "Purpose: Analysis of postnatal changes in central corneal thickness (CCT) and corneal curvature (CC) in premature infants, their relation, and their possible influence on eye growth and intraocular pressure (IOP) evaluation. Methods: CCT and CC were assessed in both eyes of 56 premature infants, born at 24 to 32 weeks of gestational age (GA), and then two or three times at post-conceptional ages (PCAs) of 28 to 42 weeks. Results: CC changed from 65.83 diopters at 28 weeks of PCA to 49.38 diopters at 42 weeks of PCA. CCT decreased from 794 to 559 μm at the same ages. The reductions of these two corneal parameters seem to be related to each other and begin immediately after birth. Conclusion: In light of the few data available in the literature, these data provide more certainty about the CCT values of premature infants. The importance of CCT and CC fast variations after premature birth concerns both the knowledge of anterior segment development and the correct evaluation of IOP in immature eyes; the influence of these two parameters on the methods of IOP evaluation could be more remarkable at the lowest PCAs.",
author = "{de Silva}, Silvana and Fulvio Parentin and Paola Michieletto and Stefano Pensiero",
year = "2011",
month = "1",
doi = "10.3928/01913913-20100318-02",
language = "English",
volume = "48",
pages = "25--29",
journal = "Journal of Pediatric Ophthalmology and Strabismus",
issn = "0191-3913",
publisher = "Slack Incorporated",
number = "1",

}

TY - JOUR

T1 - Corneal curvature and thickness development in premature infants

AU - de Silva, Silvana

AU - Parentin, Fulvio

AU - Michieletto, Paola

AU - Pensiero, Stefano

PY - 2011/1

Y1 - 2011/1

N2 - Purpose: Analysis of postnatal changes in central corneal thickness (CCT) and corneal curvature (CC) in premature infants, their relation, and their possible influence on eye growth and intraocular pressure (IOP) evaluation. Methods: CCT and CC were assessed in both eyes of 56 premature infants, born at 24 to 32 weeks of gestational age (GA), and then two or three times at post-conceptional ages (PCAs) of 28 to 42 weeks. Results: CC changed from 65.83 diopters at 28 weeks of PCA to 49.38 diopters at 42 weeks of PCA. CCT decreased from 794 to 559 μm at the same ages. The reductions of these two corneal parameters seem to be related to each other and begin immediately after birth. Conclusion: In light of the few data available in the literature, these data provide more certainty about the CCT values of premature infants. The importance of CCT and CC fast variations after premature birth concerns both the knowledge of anterior segment development and the correct evaluation of IOP in immature eyes; the influence of these two parameters on the methods of IOP evaluation could be more remarkable at the lowest PCAs.

AB - Purpose: Analysis of postnatal changes in central corneal thickness (CCT) and corneal curvature (CC) in premature infants, their relation, and their possible influence on eye growth and intraocular pressure (IOP) evaluation. Methods: CCT and CC were assessed in both eyes of 56 premature infants, born at 24 to 32 weeks of gestational age (GA), and then two or three times at post-conceptional ages (PCAs) of 28 to 42 weeks. Results: CC changed from 65.83 diopters at 28 weeks of PCA to 49.38 diopters at 42 weeks of PCA. CCT decreased from 794 to 559 μm at the same ages. The reductions of these two corneal parameters seem to be related to each other and begin immediately after birth. Conclusion: In light of the few data available in the literature, these data provide more certainty about the CCT values of premature infants. The importance of CCT and CC fast variations after premature birth concerns both the knowledge of anterior segment development and the correct evaluation of IOP in immature eyes; the influence of these two parameters on the methods of IOP evaluation could be more remarkable at the lowest PCAs.

UR - http://www.scopus.com/inward/record.url?scp=79953679279&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79953679279&partnerID=8YFLogxK

U2 - 10.3928/01913913-20100318-02

DO - 10.3928/01913913-20100318-02

M3 - Article

C2 - 20411870

AN - SCOPUS:79953679279

VL - 48

SP - 25

EP - 29

JO - Journal of Pediatric Ophthalmology and Strabismus

JF - Journal of Pediatric Ophthalmology and Strabismus

SN - 0191-3913

IS - 1

ER -