Corneal epithelial healing after photorefractive keratectomy: Analytical study

Sebastiano Serrao, Marco Lombardo

Research output: Contribution to journalArticle

Abstract

Purpose: To characterize the velocity of epithelial migration after photorefractive keratectomy (PRK) with 3 different corneal ablation patterns. Setting: Department of Ophthalmology, Catholic University of Rome, Rome, Italy. Methods: Fifteen patients (30 eyes) with mild to moderate myopia and with simple to compound myopic astigmatism were enrolled for this study. The surgical procedure consisted of standardized PRK with final smoothing performed using the Technolas Keracor 217C excimer laser. The reepithelialization process was evaluated at 0 hours, 20 hours, 40 hours, and 60 hours after surgery using a digital photo camera and custom software for measurement. Digital analysis of the images was performed. Corneal topographies were taken at 1 month, 3 months, 6 months, and 12 months after PRK. Results: The mean speed of radial migration in the 10 eyes (33%) in the low spherical ablation group was 0.087 mm/h ± 0.008 (SD). This was significantly higher than that found in the 10 eyes (33%) in the high spherical ablation group (mean speed 0.078 ± 0.007 mm/h; P

Original languageEnglish
Pages (from-to)930-937
Number of pages8
JournalJournal of Cataract and Refractive Surgery
Volume31
Issue number5
DOIs
Publication statusPublished - May 2005

ASJC Scopus subject areas

  • Ophthalmology

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