Corneometric values of non-lesional psoriasis are decreased. Influence of skin area in corneometric evaluations

Several evidences, both of structural and biochemical type, show that skin of all psoriatic patients participates in the disease. Previous studies reported that corneometric determinations obtained from nonlesional areas of patients with psoriasis were unchanged as compared to normal skin. This study analyzes the corneometric values in 20 subjects affected with plaque-type psoriasis and in 20 healthy controls. Corneometry was performed at the non-lesional skin level. Corresponding body areas were selected in normal controls. Our observations have shown that also non-lesional skin is involved in the psoriatic disease. In addition, we analyzed the corneometric values observed in 6 different skin areas of 25 healthy controls to highlight possible variations. Generally, in different localizations, the corneometric measurements were significantly different, stressing the need to take into account this variable when different groups are compared.