Coronary artery bypass graft versus percutaneous coronary intervention with drug-eluting stent implantation for diabetic patients with unprotected left main coronary artery disease: The D-DELTA registry

Emanuele Meliga, Mauro De Benedictis, Alaide Chieffo, Azeem Latib, Seung Jung Park, Young Hak Kim, Yoshinobu Onuma, Piera Capranzano, Sanda Jegere, Raj Makkar, Igor Palacios, Pawel Buszman, Marta Bande, Tarun Chakravarty, Roxana Mehran, Christoph Naber, Innocenzo Scrocca, Ronan Margey, Martin Leon, Jeffrey MosesJean Fajadet, Thierry Lefèvre, Marie Claude Morice, Andrejs Erglis, Corrado Tamburino, Ottavio Alfieri, Maria Rosa Conte, Patrick W. Serruys, Antonio Colombo

Research output: Contribution to journalArticle

Abstract

Aims: Data regarding the impact on clinical outcomes of PCI with DES implantation vs. CABG to treat unprotected left main coronary artery (ULMCA) disease in diabetic patients are still insufficient. The present study evaluated the short-term and long-term results of percutaneous and surgical revascularisation in diabetic patients with ULMCA disease in a large population. Methods and results: A total of 826 diabetic patients with ULMCA stenosis who received DES (n=520) or underwent CABG (n=306) were selected and analysed from the DELTA registry. In-hospital MACCE was significantly higher in the CABG group, mainly driven by a higher incidence of MI. At four-year follow-up, freedom from death and the composite endpoint of death, MI and cerebrovascular accident (CVA) was similar in the two treatment groups (CABG 87.4%, PCI 82.5%, p=0.124, and CABG 85.4%, PCI 78.9%, p=0.11, respectively). Conversely, freedom from TVR and MACCE was significantly higher in the CABG compared to the PCI group (CABG 95.4%, PCI 79.4%, p

Original languageEnglish
Pages (from-to)803-808
Number of pages6
JournalEuroIntervention
Volume9
Issue number7
DOIs
Publication statusPublished - Nov 2013

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Drug-Eluting Stents
Percutaneous Coronary Intervention
Coronary Artery Bypass
Registries
Coronary Artery Disease
Transplants
Coronary Stenosis
Stroke
Incidence
Population
Therapeutics

Keywords

  • Coronary artery bypass graft
  • Diabetes
  • Drug-eluting stents
  • Unprotected left main coronary artery disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Coronary artery bypass graft versus percutaneous coronary intervention with drug-eluting stent implantation for diabetic patients with unprotected left main coronary artery disease : The D-DELTA registry. / Meliga, Emanuele; De Benedictis, Mauro; Chieffo, Alaide; Latib, Azeem; Park, Seung Jung; Kim, Young Hak; Onuma, Yoshinobu; Capranzano, Piera; Jegere, Sanda; Makkar, Raj; Palacios, Igor; Buszman, Pawel; Bande, Marta; Chakravarty, Tarun; Mehran, Roxana; Naber, Christoph; Scrocca, Innocenzo; Margey, Ronan; Leon, Martin; Moses, Jeffrey; Fajadet, Jean; Lefèvre, Thierry; Morice, Marie Claude; Erglis, Andrejs; Tamburino, Corrado; Alfieri, Ottavio; Conte, Maria Rosa; Serruys, Patrick W.; Colombo, Antonio.

In: EuroIntervention, Vol. 9, No. 7, 11.2013, p. 803-808.

Research output: Contribution to journalArticle

Meliga, E, De Benedictis, M, Chieffo, A, Latib, A, Park, SJ, Kim, YH, Onuma, Y, Capranzano, P, Jegere, S, Makkar, R, Palacios, I, Buszman, P, Bande, M, Chakravarty, T, Mehran, R, Naber, C, Scrocca, I, Margey, R, Leon, M, Moses, J, Fajadet, J, Lefèvre, T, Morice, MC, Erglis, A, Tamburino, C, Alfieri, O, Conte, MR, Serruys, PW & Colombo, A 2013, 'Coronary artery bypass graft versus percutaneous coronary intervention with drug-eluting stent implantation for diabetic patients with unprotected left main coronary artery disease: The D-DELTA registry', EuroIntervention, vol. 9, no. 7, pp. 803-808. https://doi.org/10.4244/EIJV9I7A133
Meliga, Emanuele ; De Benedictis, Mauro ; Chieffo, Alaide ; Latib, Azeem ; Park, Seung Jung ; Kim, Young Hak ; Onuma, Yoshinobu ; Capranzano, Piera ; Jegere, Sanda ; Makkar, Raj ; Palacios, Igor ; Buszman, Pawel ; Bande, Marta ; Chakravarty, Tarun ; Mehran, Roxana ; Naber, Christoph ; Scrocca, Innocenzo ; Margey, Ronan ; Leon, Martin ; Moses, Jeffrey ; Fajadet, Jean ; Lefèvre, Thierry ; Morice, Marie Claude ; Erglis, Andrejs ; Tamburino, Corrado ; Alfieri, Ottavio ; Conte, Maria Rosa ; Serruys, Patrick W. ; Colombo, Antonio. / Coronary artery bypass graft versus percutaneous coronary intervention with drug-eluting stent implantation for diabetic patients with unprotected left main coronary artery disease : The D-DELTA registry. In: EuroIntervention. 2013 ; Vol. 9, No. 7. pp. 803-808.
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T1 - Coronary artery bypass graft versus percutaneous coronary intervention with drug-eluting stent implantation for diabetic patients with unprotected left main coronary artery disease

T2 - The D-DELTA registry

AU - Meliga, Emanuele

AU - De Benedictis, Mauro

AU - Chieffo, Alaide

AU - Latib, Azeem

AU - Park, Seung Jung

AU - Kim, Young Hak

AU - Onuma, Yoshinobu

AU - Capranzano, Piera

AU - Jegere, Sanda

AU - Makkar, Raj

AU - Palacios, Igor

AU - Buszman, Pawel

AU - Bande, Marta

AU - Chakravarty, Tarun

AU - Mehran, Roxana

AU - Naber, Christoph

AU - Scrocca, Innocenzo

AU - Margey, Ronan

AU - Leon, Martin

AU - Moses, Jeffrey

AU - Fajadet, Jean

AU - Lefèvre, Thierry

AU - Morice, Marie Claude

AU - Erglis, Andrejs

AU - Tamburino, Corrado

AU - Alfieri, Ottavio

AU - Conte, Maria Rosa

AU - Serruys, Patrick W.

AU - Colombo, Antonio

PY - 2013/11

Y1 - 2013/11

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KW - Coronary artery bypass graft

KW - Diabetes

KW - Drug-eluting stents

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