Coronary artery disease: Diagnostic accuracy of CT coronary angiography-a comparison of high and standard spatial resolution scanning

Gianluca Pontone, Erika Bertella, Saima Mushtaq, Monica Loguercio, Sarah Cortinovis, Andrea Baggiano, Edoardo Conte, Andrea Annoni, Alberto Formenti, Virginia Beltrama, Andrea Igoren Guaricci, Daniele Andreini

Research output: Contribution to journalArticle

Abstract

Purpose: To compare the image quality, evaluability, diagnostic accuracy, and radiation exposure of high-spatial-resolution (HR, 0.23-mm) computed tomographic (CT) coronary angiography with standard spatial resolution (SR, 0.625-mm) 64-section imaging in patients at high risk for coronary artery disease (CAD) by using invasive coronary angiography (ICA) as the reference method. Materials and Methods: Written informed consent was obtained from all patients, and the study protocol was approved by the institutional ethical committee. Patients at high risk for CAD (n = 184) who were scheduled for ICA were randomly assigned for study with SR (n = 91) or HR (n = 93) coronary CT angiography before they underwent ICA. To compare the two groups, the Student t test or Wilcoxon test were used to evaluate differences in continuous variables. The x2 test or Fisher exact test were used, as appropriate, for categorical data. The McNemar test was used to compare the diagnostic performance of coronary CT angiography versus that of ICA in each group. Results: HR coronary CT angiography showed a higher image quality score (3.7 vs 3.4, P,.001) and evaluability (97% vs 92%, P

Original languageEnglish
Pages (from-to)688-694
Number of pages7
JournalRadiology
Volume271
Issue number3
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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