Coronary artery imaging with intravascular high-frequency ultrasound

Benjamin N. Potkin, Antonio L. Bartorelli, James M. Gessert, Richard F. Neville, Yaron Almagor, William C. Roberts, Martin B. Leon

Research output: Contribution to journalArticlepeer-review


Safe and effective clinical application of new interventional therapies may require more precise imaging of atherosclerotic coronary arteries. To determine the reliability of catheter-based intravascular ultrasound as an imaging modality, a miniaturized prototype ultrasound system (1-mm transducer; center frequency, 25 MHz) was used to acquire two-dimensional, crosssectional images in 21 human coronary arteries from 13 patients studied at necropsy who had moderate-to-severe atherosclerosis. Fifty-four atherosclerotic sites imaged by ultrasound were compared with formalin-fixed and fresh histological sections of the coronary arteries with a digital video planimetry system. Ultrasound and histological measurements correlated significantly (all p

Original languageEnglish
Pages (from-to)1575-1585
Number of pages11
Issue number5
Publication statusPublished - 1990


  • Coronary artery disease
  • Ultrasound

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine


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