Abstract
Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.
| Original language | English |
|---|---|
| Article number | 413920 |
| Journal | International Journal of Endocrinology |
| Volume | 2014 |
| DOIs | |
| Publication status | Published - 2014 |
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ASJC Scopus subject areas
- Endocrine and Autonomic Systems
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Coronary heart disease in postmenopausal women with type II diabetes mellitus and the impact of estrogen replacement therapy : A narrative review. / Boukhris, Marouane; Tomasello, Salvatore Davide; Marzà, Francesco; Bregante, Sonia; Pluchinotta, Francesca Romana; Galassi, Alfredo Ruggero.
In: International Journal of Endocrinology, Vol. 2014, 413920, 2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Coronary heart disease in postmenopausal women with type II diabetes mellitus and the impact of estrogen replacement therapy
T2 - A narrative review
AU - Boukhris, Marouane
AU - Tomasello, Salvatore Davide
AU - Marzà, Francesco
AU - Bregante, Sonia
AU - Pluchinotta, Francesca Romana
AU - Galassi, Alfredo Ruggero
PY - 2014
Y1 - 2014
N2 - Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.
AB - Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.
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UR - http://www.scopus.com/inward/citedby.url?scp=84928503856&partnerID=8YFLogxK
U2 - 10.1155/2014/413920
DO - 10.1155/2014/413920
M3 - Article
VL - 2014
JO - International Journal of Endocrinology
JF - International Journal of Endocrinology
SN - 1687-8337
M1 - 413920
ER -