Coronary heart disease, type 2 diabetes mellitus and cardiovascular disease risk factors: A study on a middle-aged and elderly population

Roberto Giansanti, Rosa Anna Rabini, Fabio Romagnoli, Daniele Fumelli, Pierluigi Sorichetti, Massimo Boemi, Paolo Fumelli

Research output: Contribution to journalArticle

Abstract

The risk for all the manifestations of atherosclerotic disease is increased in patients affected by type 2 diabetes mellitus. The aim of the present work was to evaluate the prevalence of coronary heart disease (CHD) in a well-characterized middle-aged and elderly Italian diabetic population. The population studied included 3862 subjects, i.e. all the patients affected by type 2 diabetes of age ≥ 50 years attending the outpatient diabetes care unit of INRCA in Ancona (Italy) from 1 August 1997 to 31 July 1998. We collected and analysed both clinical and laboratory data by means of a computerized data base for the outpatient clinic management. The prevalence rate of CHD was 20.25% in this population. The groups with CHD and without CHD did not differ significantly with respect to age at onset of diabetes, body mass index and HbA1c levels, while patients with CHD were significantly older than patients without CHD and had a longer duration of diabetes. The prevalence of patients with hypertension (52.9 vs 63.0%, P <0.001), hypercholesterolemia (11.6 vs 14.1%, P <0.05) and hyperlipidemia (17.8 vs 23.3%, P <0.001) was significantly higher in the group of diabetic subjects affected by CHD than in patients not affected by heart ischemic disease. It might be hypothesized that the improvement of metabolic profile and the currently feasible control of non-diabetic risk factors could reduce cardiovascular disease rates in type 2 diabetic patients.

Original languageEnglish
Pages (from-to)175-182
Number of pages8
JournalArchives of Gerontology and Geriatrics
Volume29
Issue number2
DOIs
Publication statusPublished - Sep 1999

Keywords

  • Coronary heart disease
  • Hypercholesterolemia
  • Hyperlipidemia
  • Hypertension
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)

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