Embolia paradossa coronarica in un giovane paziente con forame ovale pervio, mutazione genetica pro-trombotica ed ipersensibilità all'eparina

The presence of patent forame ovale portends an increased risk of paradoxical embolism, particularly when atrial septal aneurysm is associated. The classic and most frequent clinical manifestation of paradoxical embolism through a patent forame ovale is ischemic stroke, although every vascular district in the systemic circulation may be involved. It is known that coagulation abnormalities may further promote embolisms in these patients. In this report we describe a case of coronary paradoxical embolism in a young patients with patent forame ovale and atrial septal aneurysm, prothrombotic state, and previous hypersensitivity reaction to heparin.