Coronary vasoconstriction induced by vasopressin: Production of myocardial ischemia in dogs by constriction of nondiseased small vessels

Mary F. Maturi; Sharon E. Martin; David Markle; Maret Maxwell; Cheryl R. Burruss; Edith Speir; Rodney Greene; Young Moo Ro; Dino Vitale; Michael V. Green; Seth R. Goldstein; Stephen L. Bacharach; Randolph E. Patterson

Coronary vasoconstriction induced by vasopressin: Production of myocardial ischemia in dogs by constriction of nondiseased small vessels

Mary F. Maturi, Sharon E. Martin, David Markle, Maret Maxwell, Cheryl R. Burruss, Edith Speir, Rodney Greene, Young Moo Ro, Dino Vitale, Michael V. Green, Seth R. Goldstein, Stephen L. Bacharach, Randolph E. Patterson

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Article › peer-review

Abstract

Background. We studied the effect of intracoronary administration of arginine-8-vasopressin on blood flow in nondiseased coronary arteries and determined whether this vasoconstriction was severe enough to produce ischemia in 30 dogs. Methods and Results. In group 1 (n=6), after vasopressin administration coronary blood flow was decreased by 41% (p

Original language	English
Pages (from-to)	2111-2121
Number of pages	11
Journal	Circulation
Volume	83
Issue number	6
Publication status	Published - Jun 1991

Keywords

Coronary arteries
Cyclooxygenase blockade
Ibuprofen
Intramyocardial pH
Left ventricular ejection fraction
Myocardial ischemia
Prostaglandins
Radionuclide angiography
Vasoconstriction
Vasopressin

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

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Coronary vasoconstriction induced by vasopressin : Production of myocardial ischemia in dogs by constriction of nondiseased small vessels. / Maturi, Mary F.; Martin, Sharon E.; Markle, David; Maxwell, Maret; Burruss, Cheryl R.; Speir, Edith; Greene, Rodney; Ro, Young Moo; Vitale, Dino; Green, Michael V.; Goldstein, Seth R.; Bacharach, Stephen L.; Patterson, Randolph E.

In: Circulation, Vol. 83, No. 6, 06.1991, p. 2111-2121.

Research output: Contribution to journal › Article › peer-review

Maturi, Mary F. ; Martin, Sharon E. ; Markle, David ; Maxwell, Maret ; Burruss, Cheryl R. ; Speir, Edith ; Greene, Rodney ; Ro, Young Moo ; Vitale, Dino ; Green, Michael V. ; Goldstein, Seth R. ; Bacharach, Stephen L. ; Patterson, Randolph E. / Coronary vasoconstriction induced by vasopressin : Production of myocardial ischemia in dogs by constriction of nondiseased small vessels. In: Circulation. 1991 ; Vol. 83, No. 6. pp. 2111-2121.

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title = "Coronary vasoconstriction induced by vasopressin: Production of myocardial ischemia in dogs by constriction of nondiseased small vessels",

abstract = "Background. We studied the effect of intracoronary administration of arginine-8-vasopressin on blood flow in nondiseased coronary arteries and determined whether this vasoconstriction was severe enough to produce ischemia in 30 dogs. Methods and Results. In group 1 (n=6), after vasopressin administration coronary blood flow was decreased by 41% (p",

keywords = "Coronary arteries, Cyclooxygenase blockade, Ibuprofen, Intramyocardial pH, Left ventricular ejection fraction, Myocardial ischemia, Prostaglandins, Radionuclide angiography, Vasoconstriction, Vasopressin",

author = "Maturi, {Mary F.} and Martin, {Sharon E.} and David Markle and Maret Maxwell and Burruss, {Cheryl R.} and Edith Speir and Rodney Greene and Ro, {Young Moo} and Dino Vitale and Green, {Michael V.} and Goldstein, {Seth R.} and Bacharach, {Stephen L.} and Patterson, {Randolph E.}",

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AU - Maturi, Mary F.

AU - Martin, Sharon E.

AU - Markle, David

AU - Maxwell, Maret

AU - Burruss, Cheryl R.

AU - Speir, Edith

AU - Greene, Rodney

AU - Ro, Young Moo

AU - Vitale, Dino

AU - Green, Michael V.

AU - Goldstein, Seth R.

AU - Bacharach, Stephen L.

AU - Patterson, Randolph E.

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AB - Background. We studied the effect of intracoronary administration of arginine-8-vasopressin on blood flow in nondiseased coronary arteries and determined whether this vasoconstriction was severe enough to produce ischemia in 30 dogs. Methods and Results. In group 1 (n=6), after vasopressin administration coronary blood flow was decreased by 41% (p

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KW - Cyclooxygenase blockade

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KW - Intramyocardial pH

KW - Left ventricular ejection fraction

KW - Myocardial ischemia

KW - Prostaglandins

KW - Radionuclide angiography

KW - Vasoconstriction

KW - Vasopressin

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