Correlates of hormone replacement therapy use in Italian women, 1992- 1996

Francesca Chiaffarino, Fabio Parazzini, Carlo La Vecchia, Massimiliano Maria Bianchi, Guido Benzi, Elena Ricci, Vito Chiantera

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objectives: We analyzed the determinants of hormonal replacement therapy (HRT) use in Italy for the period 1992-1996, using data from a framework of case-control studies of colon and rectal neoplasm. Methods: A total of 1574 women aged 45-74 years were considered. This group comprised women with acute, non neoplastic, non-hormone-related diseases admitted to a network of hospitals in six areas of Italy. Results: A total of 146 women (8.5%) reported ever HRT use. The multivariate odds ratio (OR) of ever use was 1.6 (95% CI 1.0-2.6) for women with 12 years of education or more, compared with those with 2 trend 3.5, P=0.06). Ever HRT users were more frequently smokers. HRT use was more frequent in women reporting surgical menopause (OR=2.7) than those with natural menopause. Among post menopausal women, HRT use was related with early age at menopause (χ2 trend 4.6, P=0.03). HRT use was more common among women reporting lower body mass index (BMI) both at interview and at age 30 years and the difference between current BMI and BMI at age 30 years, was not related with HRT use. Conclusions: Women of higher socioeconomic status or education reported more frequent HRT use and nulliparae and smokers were also more likely to use HRT. Further HRT use was directly associated with early age at menopause and surgical menopause and inversely related with measures of body weight.

Original languageEnglish
Pages (from-to)107-115
Number of pages9
JournalMaturitas
Volume33
Issue number2
DOIs
Publication statusPublished - Oct 24 1999

Fingerprint

Hormone Replacement Therapy
Education
Hormones
Menopause
Therapeutics
Body Mass Index
Italy
Odds Ratio
Body Weights and Measures
Rectal Neoplasms
Social Class
Colonic Neoplasms
Case-Control Studies
Interviews

Keywords

  • Determinants
  • Hormone replacement therapy
  • Use

ASJC Scopus subject areas

  • Ageing
  • Obstetrics and Gynaecology

Cite this

Correlates of hormone replacement therapy use in Italian women, 1992- 1996. / Chiaffarino, Francesca; Parazzini, Fabio; La Vecchia, Carlo; Bianchi, Massimiliano Maria; Benzi, Guido; Ricci, Elena; Chiantera, Vito.

In: Maturitas, Vol. 33, No. 2, 24.10.1999, p. 107-115.

Research output: Contribution to journalArticle

Chiaffarino, F, Parazzini, F, La Vecchia, C, Bianchi, MM, Benzi, G, Ricci, E & Chiantera, V 1999, 'Correlates of hormone replacement therapy use in Italian women, 1992- 1996', Maturitas, vol. 33, no. 2, pp. 107-115. https://doi.org/10.1016/S0378-5122(99)00055-9
Chiaffarino, Francesca ; Parazzini, Fabio ; La Vecchia, Carlo ; Bianchi, Massimiliano Maria ; Benzi, Guido ; Ricci, Elena ; Chiantera, Vito. / Correlates of hormone replacement therapy use in Italian women, 1992- 1996. In: Maturitas. 1999 ; Vol. 33, No. 2. pp. 107-115.
@article{ea5e3e283fb34afa9bf9623539cd6a5d,
title = "Correlates of hormone replacement therapy use in Italian women, 1992- 1996",
abstract = "Objectives: We analyzed the determinants of hormonal replacement therapy (HRT) use in Italy for the period 1992-1996, using data from a framework of case-control studies of colon and rectal neoplasm. Methods: A total of 1574 women aged 45-74 years were considered. This group comprised women with acute, non neoplastic, non-hormone-related diseases admitted to a network of hospitals in six areas of Italy. Results: A total of 146 women (8.5{\%}) reported ever HRT use. The multivariate odds ratio (OR) of ever use was 1.6 (95{\%} CI 1.0-2.6) for women with 12 years of education or more, compared with those with 2 trend 3.5, P=0.06). Ever HRT users were more frequently smokers. HRT use was more frequent in women reporting surgical menopause (OR=2.7) than those with natural menopause. Among post menopausal women, HRT use was related with early age at menopause (χ2 trend 4.6, P=0.03). HRT use was more common among women reporting lower body mass index (BMI) both at interview and at age 30 years and the difference between current BMI and BMI at age 30 years, was not related with HRT use. Conclusions: Women of higher socioeconomic status or education reported more frequent HRT use and nulliparae and smokers were also more likely to use HRT. Further HRT use was directly associated with early age at menopause and surgical menopause and inversely related with measures of body weight.",
keywords = "Determinants, Hormone replacement therapy, Use",
author = "Francesca Chiaffarino and Fabio Parazzini and {La Vecchia}, Carlo and Bianchi, {Massimiliano Maria} and Guido Benzi and Elena Ricci and Vito Chiantera",
year = "1999",
month = "10",
day = "24",
doi = "10.1016/S0378-5122(99)00055-9",
language = "English",
volume = "33",
pages = "107--115",
journal = "Maturitas",
issn = "0378-5122",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Correlates of hormone replacement therapy use in Italian women, 1992- 1996

AU - Chiaffarino, Francesca

AU - Parazzini, Fabio

AU - La Vecchia, Carlo

AU - Bianchi, Massimiliano Maria

AU - Benzi, Guido

AU - Ricci, Elena

AU - Chiantera, Vito

PY - 1999/10/24

Y1 - 1999/10/24

N2 - Objectives: We analyzed the determinants of hormonal replacement therapy (HRT) use in Italy for the period 1992-1996, using data from a framework of case-control studies of colon and rectal neoplasm. Methods: A total of 1574 women aged 45-74 years were considered. This group comprised women with acute, non neoplastic, non-hormone-related diseases admitted to a network of hospitals in six areas of Italy. Results: A total of 146 women (8.5%) reported ever HRT use. The multivariate odds ratio (OR) of ever use was 1.6 (95% CI 1.0-2.6) for women with 12 years of education or more, compared with those with 2 trend 3.5, P=0.06). Ever HRT users were more frequently smokers. HRT use was more frequent in women reporting surgical menopause (OR=2.7) than those with natural menopause. Among post menopausal women, HRT use was related with early age at menopause (χ2 trend 4.6, P=0.03). HRT use was more common among women reporting lower body mass index (BMI) both at interview and at age 30 years and the difference between current BMI and BMI at age 30 years, was not related with HRT use. Conclusions: Women of higher socioeconomic status or education reported more frequent HRT use and nulliparae and smokers were also more likely to use HRT. Further HRT use was directly associated with early age at menopause and surgical menopause and inversely related with measures of body weight.

AB - Objectives: We analyzed the determinants of hormonal replacement therapy (HRT) use in Italy for the period 1992-1996, using data from a framework of case-control studies of colon and rectal neoplasm. Methods: A total of 1574 women aged 45-74 years were considered. This group comprised women with acute, non neoplastic, non-hormone-related diseases admitted to a network of hospitals in six areas of Italy. Results: A total of 146 women (8.5%) reported ever HRT use. The multivariate odds ratio (OR) of ever use was 1.6 (95% CI 1.0-2.6) for women with 12 years of education or more, compared with those with 2 trend 3.5, P=0.06). Ever HRT users were more frequently smokers. HRT use was more frequent in women reporting surgical menopause (OR=2.7) than those with natural menopause. Among post menopausal women, HRT use was related with early age at menopause (χ2 trend 4.6, P=0.03). HRT use was more common among women reporting lower body mass index (BMI) both at interview and at age 30 years and the difference between current BMI and BMI at age 30 years, was not related with HRT use. Conclusions: Women of higher socioeconomic status or education reported more frequent HRT use and nulliparae and smokers were also more likely to use HRT. Further HRT use was directly associated with early age at menopause and surgical menopause and inversely related with measures of body weight.

KW - Determinants

KW - Hormone replacement therapy

KW - Use

UR - http://www.scopus.com/inward/record.url?scp=0032709612&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032709612&partnerID=8YFLogxK

U2 - 10.1016/S0378-5122(99)00055-9

DO - 10.1016/S0378-5122(99)00055-9

M3 - Article

C2 - 10597874

AN - SCOPUS:0032709612

VL - 33

SP - 107

EP - 115

JO - Maturitas

JF - Maturitas

SN - 0378-5122

IS - 2

ER -