Abstract
Impaired endothelial responsiveness to specific vasodilator stimuli has been used as a surrogate marker of cardiovascular risk. Multiple methods allow testing endothelial responses in both microvessels and conduit arteries, but it is still unclear whether there is a relationship in endothelial function between these two different vascular beds. Twenty-five healthy young non smoking male volunteers (age range 24-45) were enrolled. Radial (conduit) artery (endothelium-dependent) flow-mediated dilation (FMD), microvascular cutaneous reactive hyperemia (using laser Doppler) and acetylcholine-induced microvascular vasodilation (laser Doppler iontophoresis) were measured. Data were analyzed in a randomized fashion in order to test the existence of a correlation among these measures of endothelium (in)dependent vasodilation. Conduit artery FMD showed a negative correlation with resting radial artery diameter (R=0.44, P
| Original language | English |
|---|---|
| Pages (from-to) | 509-515 |
| Number of pages | 7 |
| Journal | Clinical Hemorheology and Microcirculation |
| Volume | 35 |
| Issue number | 4 |
| Publication status | Published - 2006 |
Fingerprint
ASJC Scopus subject areas
- Hematology
- Physiology
Cite this
Correlation analysis between different parameters of conduit artery and microvascular vasodilation. / Gori, Tommaso; Di Stolfo, Giuseppe; Sicuro, Silvia; Dragoni, Saverio; Lisi, Monica; Parker, John D.; Forconi, Sandro.
In: Clinical Hemorheology and Microcirculation, Vol. 35, No. 4, 2006, p. 509-515.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Correlation analysis between different parameters of conduit artery and microvascular vasodilation
AU - Gori, Tommaso
AU - Di Stolfo, Giuseppe
AU - Sicuro, Silvia
AU - Dragoni, Saverio
AU - Lisi, Monica
AU - Parker, John D.
AU - Forconi, Sandro
PY - 2006
Y1 - 2006
N2 - Impaired endothelial responsiveness to specific vasodilator stimuli has been used as a surrogate marker of cardiovascular risk. Multiple methods allow testing endothelial responses in both microvessels and conduit arteries, but it is still unclear whether there is a relationship in endothelial function between these two different vascular beds. Twenty-five healthy young non smoking male volunteers (age range 24-45) were enrolled. Radial (conduit) artery (endothelium-dependent) flow-mediated dilation (FMD), microvascular cutaneous reactive hyperemia (using laser Doppler) and acetylcholine-induced microvascular vasodilation (laser Doppler iontophoresis) were measured. Data were analyzed in a randomized fashion in order to test the existence of a correlation among these measures of endothelium (in)dependent vasodilation. Conduit artery FMD showed a negative correlation with resting radial artery diameter (R=0.44, P
AB - Impaired endothelial responsiveness to specific vasodilator stimuli has been used as a surrogate marker of cardiovascular risk. Multiple methods allow testing endothelial responses in both microvessels and conduit arteries, but it is still unclear whether there is a relationship in endothelial function between these two different vascular beds. Twenty-five healthy young non smoking male volunteers (age range 24-45) were enrolled. Radial (conduit) artery (endothelium-dependent) flow-mediated dilation (FMD), microvascular cutaneous reactive hyperemia (using laser Doppler) and acetylcholine-induced microvascular vasodilation (laser Doppler iontophoresis) were measured. Data were analyzed in a randomized fashion in order to test the existence of a correlation among these measures of endothelium (in)dependent vasodilation. Conduit artery FMD showed a negative correlation with resting radial artery diameter (R=0.44, P
UR - http://www.scopus.com/inward/record.url?scp=33751370945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33751370945&partnerID=8YFLogxK
M3 - Article
C2 - 17148850
AN - SCOPUS:33751370945
VL - 35
SP - 509
EP - 515
JO - Clinical Hemorheology and Microcirculation
JF - Clinical Hemorheology and Microcirculation
SN - 1386-0291
IS - 4
ER -