Correlation between, clinical, biochemical, color doppler ultrasound thyroid parameters, and CXCL-10 in autoimmune thyroid diseases

Giovanni Corona, Carlo Biagini, Mario Rotondi, Andrea Bonamano, Nadia Cremonini, Luisa Petrone, Barbara Conforti, Gianni Forti, Mario Serio

Research output: Contribution to journalArticle

Abstract

Objective: the aim of present study is to determine possible contributions of INF-γ inducible chemochine CXCL-10 in the thyroid color doppler ultrasound (CDU) parameters typical of autoimmune disorders. Methods: we studied a consecutive series of 25 patients with autoimmune thyroid disease and 10 healthy control subjects. All subjects underwent a thyroid CDU examination by the same investigator, who was unaware of the laboratory values at the time of the examination. Moreover, all subjects underwent a clinical evaluation, CXCL-10 and thyroid hormonal assessment. Results: CXCL-10 levels were significantly higher in patients with autoimmune diseases and as well as in subjects with an increased thyroid vascularization at CDU. Moreover, CXCL-10 levels were significantly (p

Original languageEnglish
Pages (from-to)345-350
Number of pages6
JournalEndocrine Journal
Volume55
Issue number2
DOIs
Publication statusPublished - 2008

Keywords

  • Autoimmune thyroid diseases
  • Chemokines
  • CXCL-10
  • Thyroid color doppler ultrasound

ASJC Scopus subject areas

  • Endocrinology

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