TY - JOUR
T1 - Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A
AU - Padua, Luca
AU - Shy, Michael E.
AU - Aprile, Irene
AU - Cavallaro, Tiziana
AU - Pareyson, Davide
AU - Quattrone, Aldo
AU - Rizzuto, Nicolo
AU - Vita, Giuseppe
AU - Tonali, Pietro
AU - Schenone, Angelo
PY - 2008/3
Y1 - 2008/3
N2 - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.
AB - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.
KW - Charcot-Marie-Tooth type 1A
KW - Neurophysiology
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=40849092774&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40849092774&partnerID=8YFLogxK
U2 - 10.1111/j.1529-8027.2008.00159.x
DO - 10.1111/j.1529-8027.2008.00159.x
M3 - Article
C2 - 18346232
AN - SCOPUS:40849092774
VL - 13
SP - 64
EP - 70
JO - Journal of the Peripheral Nervous System
JF - Journal of the Peripheral Nervous System
SN - 1085-9489
IS - 1
ER -