Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

Luca Padua; Michael E. Shy; Irene Aprile; Tiziana Cavallaro; Davide Pareyson; Aldo Quattrone; Nicolo Rizzuto; Giuseppe Vita; Pietro Tonali; Angelo Schenone

doi:10.1111/j.1529-8027.2008.00159.x

Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

Luca Padua, Michael E. Shy, Irene Aprile, Tiziana Cavallaro, Davide Pareyson, Aldo Quattrone, Nicolo Rizzuto, Giuseppe Vita, Pietro Tonali, Angelo Schenone

Research output: Contribution to journal › Article › peer-review

Abstract

Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

Original language	English
Pages (from-to)	64-70
Number of pages	7
Journal	Journal of the Peripheral Nervous System
Volume	13
Issue number	1
DOIs	https://doi.org/10.1111/j.1529-8027.2008.00159.x
Publication status	Published - Mar 2008

Keywords

Charcot-Marie-Tooth type 1A
Neurophysiology
Quality of life

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

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10.1111/j.1529-8027.2008.00159.x

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Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A. / Padua, Luca; Shy, Michael E.; Aprile, Irene; Cavallaro, Tiziana; Pareyson, Davide; Quattrone, Aldo; Rizzuto, Nicolo; Vita, Giuseppe; Tonali, Pietro; Schenone, Angelo.

In: Journal of the Peripheral Nervous System, Vol. 13, No. 1, 03.2008, p. 64-70.

Research output: Contribution to journal › Article › peer-review

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abstract = "Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.",

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AU - Pareyson, Davide

AU - Quattrone, Aldo

AU - Rizzuto, Nicolo

AU - Vita, Giuseppe

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AU - Schenone, Angelo

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Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

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Keywords

ASJC Scopus subject areas

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