Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

Luca Padua; Michael E. Shy; Irene Aprile; Tiziana Cavallaro; Davide Pareyson; Aldo Quattrone; Nicolo Rizzuto; Giuseppe Vita; Pietro Tonali; Angelo Schenone

doi:10.1111/j.1529-8027.2008.00159.x

Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

Luca Padua, Michael E. Shy, Irene Aprile, Tiziana Cavallaro, Davide Pareyson, Aldo Quattrone, Nicolo Rizzuto, Giuseppe Vita, Pietro Tonali, Angelo Schenone

Research output: Contribution to journal › Article

Abstract

Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

Original language	English
Pages (from-to)	64-70
Number of pages	7
Journal	Journal of the Peripheral Nervous System
Volume	13
Issue number	1
DOIs	https://doi.org/10.1111/j.1529-8027.2008.00159.x
Publication status	Published - Mar 2008

Keywords

Charcot-Marie-Tooth type 1A
Neurophysiology
Quality of life

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

Access to Document

10.1111/j.1529-8027.2008.00159.x

Fingerprint Dive into the research topics of 'Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A'. Together they form a unique fingerprint.

Cite this

Padua, L., Shy, M. E., Aprile, I., Cavallaro, T., Pareyson, D., Quattrone, A., Rizzuto, N., Vita, G., Tonali, P., & Schenone, A. (2008). Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A. Journal of the Peripheral Nervous System, 13(1), 64-70. https://doi.org/10.1111/j.1529-8027.2008.00159.x

Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A. / Padua, Luca; Shy, Michael E.; Aprile, Irene; Cavallaro, Tiziana; Pareyson, Davide; Quattrone, Aldo; Rizzuto, Nicolo; Vita, Giuseppe; Tonali, Pietro; Schenone, Angelo.

In: Journal of the Peripheral Nervous System, Vol. 13, No. 1, 03.2008, p. 64-70.

Research output: Contribution to journal › Article

@article{a0190fe79483443cb230bc0ceccccc0d,

title = "Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A",

abstract = "Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.",

keywords = "Charcot-Marie-Tooth type 1A, Neurophysiology, Quality of life",

author = "Luca Padua and Shy, {Michael E.} and Irene Aprile and Tiziana Cavallaro and Davide Pareyson and Aldo Quattrone and Nicolo Rizzuto and Giuseppe Vita and Pietro Tonali and Angelo Schenone",

year = "2008",

month = mar,

doi = "10.1111/j.1529-8027.2008.00159.x",

language = "English",

volume = "13",

pages = "64--70",

journal = "Journal of the Peripheral Nervous System",

issn = "1085-9489",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A

AU - Padua, Luca

AU - Shy, Michael E.

AU - Aprile, Irene

AU - Cavallaro, Tiziana

AU - Pareyson, Davide

AU - Quattrone, Aldo

AU - Rizzuto, Nicolo

AU - Vita, Giuseppe

AU - Tonali, Pietro

AU - Schenone, Angelo

PY - 2008/3

Y1 - 2008/3

N2 - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

AB - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.

KW - Charcot-Marie-Tooth type 1A

KW - Neurophysiology

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=40849092774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=40849092774&partnerID=8YFLogxK

U2 - 10.1111/j.1529-8027.2008.00159.x

DO - 10.1111/j.1529-8027.2008.00159.x

M3 - Article

C2 - 18346232

AN - SCOPUS:40849092774

VL - 13

SP - 64

EP - 70

JO - Journal of the Peripheral Nervous System

JF - Journal of the Peripheral Nervous System

SN - 1085-9489

IS - 1

ER -