Correlation between collateral ventilation and interlobar lung fissures

Daniele Diso, Marco Anile, Carolina Carillo, Franco Ruberto, Miriam Patella, R. Emanuele, Francesco Fraioli, Tiziano De Giacomo, Sara Mantovani, Erino Rendina, Federico Venuta

Research output: Contribution to journalArticle

Abstract

Background: New bronchoscopic techniques for end-stage emphysema treatment are nowadays available; the presence of interlobar collateral ventilation (CV) and interlobar lung fissures (ILF) is crucial for patient selection.

Objectives: Assessment of these variables has been reported previously, but it has never been anatomically validated in vivo. This is the purpose of our study.

Methods: Twenty-one patients undergoing lung resection for lung cancer were prospectively enrolled in this study. At operation, CV was assessed by the Chartis ® catheter system. ILF completeness at high-resolution computed tomography (HRCT) was retrospectively reviewed. The ILF status at HRCT and at surgery was compared; furthermore, the relationship between CV and ILF status was assessed.

Results: At HRCT, ILF were incomplete in 18 cases; at catheter evaluation, CV was present in 11 cases; 15 patients had incomplete ILF at operation. HRCT specificity, sensitivity and accuracy were 33, 93 and 76% compared with ILF status at surgery. HRCT accuracy was 90% on the right and 63% on the left. We demonstrated a high grade of probability of CV presence and incomplete ILF at surgery (odds ratio = 10.0).

Conclusions: There is a correlation between ILF status and CV. Both catheter evaluation of CV and HRCT assessment of ILF show some limitations. However, the cumulative information provided by these techniques allows to reliably assess the anatomical ILF status.

Original languageEnglish
Pages (from-to)315-319
Number of pages5
JournalRespiration
Volume88
Issue number4
DOIs
Publication statusPublished - Nov 7 2014

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Keywords

  • Airway bypass
  • Bronchoscopic lung volume reduction
  • Collateral lung ventilation
  • Emphysema
  • Interlobar fissures

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Diso, D., Anile, M., Carillo, C., Ruberto, F., Patella, M., Emanuele, R., Fraioli, F., De Giacomo, T., Mantovani, S., Rendina, E., & Venuta, F. (2014). Correlation between collateral ventilation and interlobar lung fissures. Respiration, 88(4), 315-319. https://doi.org/10.1159/000363538