TY - JOUR
T1 - Correlation between depression, quality of life and clinical severity in patients with hidradenitis suppurativa
AU - Sampogna, Francesca
AU - Fania, Luca
AU - Mastroeni, Simona
AU - Fusari, Roberta
AU - Napolitano, Monica
AU - Ciccone, Davide
AU - Mazzanti, Cinzia
AU - Pallotta, Sabatino
AU - Panebianco, Annarita
AU - Abeni, Damiano
N1 - Funding Information:
This study was supported in part by the “Progetto Ricerca Corrente 2019” of the Italian Ministry of Health, Rome, Italy.
Publisher Copyright:
© 2020, Medical Journals/Acta D-V. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Depression is frequent in patients with hidradenitis suppurativa. However, its relationship with quality of life and clinical severity needs further investiga-tion. In this cross-sectional study, 341 adult, consecu-tive patients with hidradenitis suppurativa completed the 12-item General Health Questionnaire (GHQ-12), which has been shown to be able to identify cases of major depressive disorder in dermatological patients. The frequency of depression in hidradenitis suppura-tiva patients was 29.0%. In patients with depression, severity (International Hidradenitis Suppurativa Severity Score System (IHS4)), quality of life (Skindex-17; Dermatology Life Quality Index (DLQI)), and health status (36-item Short Form Health Survey (SF-36)) were significantly worse compared with patients with no depression. The highest linear correlation was ob-served between GHQ-12 and the psychosocial scale of the Skindex-17 and the SF-36 mental scale. In cont-rast, correlation between GHQ-12 and clinical severity was poor. Depression is an important comorbidity in hidradenitis suppurativa, which is strongly associated with impairment in quality of life, but not linearly cor-related with clinical severity.
AB - Depression is frequent in patients with hidradenitis suppurativa. However, its relationship with quality of life and clinical severity needs further investiga-tion. In this cross-sectional study, 341 adult, consecu-tive patients with hidradenitis suppurativa completed the 12-item General Health Questionnaire (GHQ-12), which has been shown to be able to identify cases of major depressive disorder in dermatological patients. The frequency of depression in hidradenitis suppura-tiva patients was 29.0%. In patients with depression, severity (International Hidradenitis Suppurativa Severity Score System (IHS4)), quality of life (Skindex-17; Dermatology Life Quality Index (DLQI)), and health status (36-item Short Form Health Survey (SF-36)) were significantly worse compared with patients with no depression. The highest linear correlation was ob-served between GHQ-12 and the psychosocial scale of the Skindex-17 and the SF-36 mental scale. In cont-rast, correlation between GHQ-12 and clinical severity was poor. Depression is an important comorbidity in hidradenitis suppurativa, which is strongly associated with impairment in quality of life, but not linearly cor-related with clinical severity.
KW - 12-item General Health Questionnaire
KW - Acne inversa
KW - Clinical severity
KW - Depression
KW - Hidradenitis suppurativa
KW - Quality of life
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U2 - 10.2340/00015555-3647
DO - 10.2340/00015555-3647
M3 - Article
C2 - 32985674
AN - SCOPUS:85096152434
VL - 100
SP - 1
EP - 6
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 18
M1 - adv00319
ER -