Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection

Raffaele Bruno; Paolo Sacchi; Serena Cima; Laura Maiocchi; Savino F A Patruno; Catherine Klersy; Giorgio Barbarini; Valentina Zuccaro; Calogero Camma; Gaetano Filice

doi:10.1016/j.dld.2011.03.009

Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection

Raffaele Bruno, Paolo Sacchi, Serena Cima, Laura Maiocchi, Savino F A Patruno, Catherine Klersy, Giorgio Barbarini, Valentina Zuccaro, Calogero Camma, Gaetano Filice

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Background/Aims: Assessment of liver fibrosis is crucial in HIV/HCV coinfected patients, in whom metabolic disturbances are frequent. Aims of this study were to analyse the association of two non-invasive liver fibrosis evaluation methods, liver stiffness measurement and FIB4, and their correlation with metabolic parameters. Methods: This was a single centre cross-sectional study. All patients underwent biochemical and virological assessment, FIB4 score, HOMA and transient elastography. Results: Seventy-five patients were evaluated. Liver stiffness values positively correlated with FIB4 (R=0.62; p

Original language	English
Pages (from-to)	575-578
Number of pages	4
Journal	Digestive and Liver Disease
Volume	43
Issue number	7
DOIs	https://doi.org/10.1016/j.dld.2011.03.009
Publication status	Published - Jul 2011

Keywords

FIB4
HIV-HCV
HOMA
Liver stiffness

ASJC Scopus subject areas

Gastroenterology
Hepatology

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10.1016/j.dld.2011.03.009

Cite this

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title = "Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection",

abstract = "Background/Aims: Assessment of liver fibrosis is crucial in HIV/HCV coinfected patients, in whom metabolic disturbances are frequent. Aims of this study were to analyse the association of two non-invasive liver fibrosis evaluation methods, liver stiffness measurement and FIB4, and their correlation with metabolic parameters. Methods: This was a single centre cross-sectional study. All patients underwent biochemical and virological assessment, FIB4 score, HOMA and transient elastography. Results: Seventy-five patients were evaluated. Liver stiffness values positively correlated with FIB4 (R=0.62; p",

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T1 - Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection

AU - Bruno, Raffaele

AU - Sacchi, Paolo

AU - Cima, Serena

AU - Maiocchi, Laura

AU - Patruno, Savino F A

AU - Klersy, Catherine

AU - Barbarini, Giorgio

AU - Zuccaro, Valentina

AU - Camma, Calogero

AU - Filice, Gaetano

PY - 2011/7

Y1 - 2011/7

N2 - Background/Aims: Assessment of liver fibrosis is crucial in HIV/HCV coinfected patients, in whom metabolic disturbances are frequent. Aims of this study were to analyse the association of two non-invasive liver fibrosis evaluation methods, liver stiffness measurement and FIB4, and their correlation with metabolic parameters. Methods: This was a single centre cross-sectional study. All patients underwent biochemical and virological assessment, FIB4 score, HOMA and transient elastography. Results: Seventy-five patients were evaluated. Liver stiffness values positively correlated with FIB4 (R=0.62; p

AB - Background/Aims: Assessment of liver fibrosis is crucial in HIV/HCV coinfected patients, in whom metabolic disturbances are frequent. Aims of this study were to analyse the association of two non-invasive liver fibrosis evaluation methods, liver stiffness measurement and FIB4, and their correlation with metabolic parameters. Methods: This was a single centre cross-sectional study. All patients underwent biochemical and virological assessment, FIB4 score, HOMA and transient elastography. Results: Seventy-five patients were evaluated. Liver stiffness values positively correlated with FIB4 (R=0.62; p

KW - FIB4

KW - HIV-HCV

KW - HOMA

KW - Liver stiffness

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Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection

Abstract

Keywords

ASJC Scopus subject areas

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