Correlation between FIB4, liver stiffness and metabolic parameters in patients with HIV and hepatitis C virus co-infection

Raffaele Bruno, Paolo Sacchi, Serena Cima, Laura Maiocchi, Savino F A Patruno, Catherine Klersy, Giorgio Barbarini, Valentina Zuccaro, Calogero Camma, Gaetano Filice

Research output: Contribution to journalArticlepeer-review

Abstract

Background/Aims: Assessment of liver fibrosis is crucial in HIV/HCV coinfected patients, in whom metabolic disturbances are frequent. Aims of this study were to analyse the association of two non-invasive liver fibrosis evaluation methods, liver stiffness measurement and FIB4, and their correlation with metabolic parameters. Methods: This was a single centre cross-sectional study. All patients underwent biochemical and virological assessment, FIB4 score, HOMA and transient elastography. Results: Seventy-five patients were evaluated. Liver stiffness values positively correlated with FIB4 (R=0.62; p

Original languageEnglish
Pages (from-to)575-578
Number of pages4
JournalDigestive and Liver Disease
Volume43
Issue number7
DOIs
Publication statusPublished - Jul 2011

Keywords

  • FIB4
  • HIV-HCV
  • HOMA
  • Liver stiffness

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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