Correlation between liver cirrhosis and benign prostatic hyperplasia: A morphological study

B. Frea, S. Annoscia, G. Stanta, C. Lozzi, G. Carmignani

Research output: Contribution to journalArticlepeer-review


In elderly males hormonal changes occur, that are believed to cause benign prostatic hyperplasia (BPH). These are decreased testosterone production, an increased testosterone SHBG and a slightly increased estradiol production. Liver cirrhosis in males causes similar endocrine changes. We carried out a post mortem study evaluating the prostates of 51 men who died with liver cirrhosis compared with a similar group without any hepatic disease. The occurrence of BPH in cirrhotic subjects was diminished and delayed compared to total population. Furthermore in cirrhotic men BPH is more common as early nodular hyperplasia (early stage) or stromal hyperplasia (suggesting estrogenic prevalence), while in the general population stromal and epithelial hyperplasia (androgenic stimulation), were almost equally present.

Original languageEnglish
Pages (from-to)311-314
Number of pages4
JournalUrological Research
Issue number5
Publication statusPublished - Sep 1987


  • Alcoholic liver cirrhosis
  • Benign porstatic hyperplasia (BPH)
  • Epithelial hyperplasia
  • Stromal hyperplasia

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Correlation between liver cirrhosis and benign prostatic hyperplasia: A morphological study'. Together they form a unique fingerprint.

Cite this