Correlation between PAH airborne concentration and PAH-DNA adducts levels in coke-oven workers

G. Assennato, G. M. Ferris, V. Foà, P. Strickland, M. Poirier, L. Pozzoli, D. Cottica

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In order to evaluate the correlation between peripheral blood leukocyte DNA adducts as an indicator of exposure to polycyclic aromatic hydrocarbons (PAH) and the airborne contamination of PAH at the work places, a survey of a cohort of coke-oven workers has been carried out. In each workplace, total and specific PAH airborne concentrations were measured. Among the job title groups, the highest proportion of subjects with levels of adducts above the detection limit and the highest mean value were observed in the door-operators. The correlation between median values of environmental benzo(a)pyrene concentration and mean values of adducts concentration support the fact that the maintenance workers group has a higher relative risk (RR) to have detectable level of PAH-adducts, which is estimated to be 1.84 for an increase of 1 μg/m3 of benzo(a)pyrene.

Original languageEnglish
JournalInternational Archives of Occupational and Environmental Health
Volume65
Issue number1 Supplement
DOIs
Publication statusPublished - Jan 1993

Fingerprint

Coke
Polycyclic Aromatic Hydrocarbons
Benzo(a)pyrene
Workplace
DNA Adducts
Limit of Detection
Leukocytes
Maintenance
polycyclic aromatic hydrocarbons-DNA adduct

Keywords

  • Coke-oven workers
  • DNA-adducts
  • PAHs

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Correlation between PAH airborne concentration and PAH-DNA adducts levels in coke-oven workers. / Assennato, G.; Ferris, G. M.; Foà, V.; Strickland, P.; Poirier, M.; Pozzoli, L.; Cottica, D.

In: International Archives of Occupational and Environmental Health, Vol. 65, No. 1 Supplement, 01.1993.

Research output: Contribution to journalArticle

Assennato, G. ; Ferris, G. M. ; Foà, V. ; Strickland, P. ; Poirier, M. ; Pozzoli, L. ; Cottica, D. / Correlation between PAH airborne concentration and PAH-DNA adducts levels in coke-oven workers. In: International Archives of Occupational and Environmental Health. 1993 ; Vol. 65, No. 1 Supplement.
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