Correlation between presence of allodynia and sleep quality in migraineurs

C. Lovati, D. D'Amico, P. Bertora, E. Raimondi, S. Rosa, M. Zardoni, G. Bussone, C. Mariani

Research output: Contribution to journalArticle

Abstract

Cutaneous allodynia is a frequent complaint in migraine patients, possibly induced by central sensitisation of trigeminal nucleus. The objective of this study is to investigate if sleep quality is related to the presence of migraine-associated allodynia. A total of 175 consecutive migraineurs were included, 124 with episodic and 51 with chronic forms. As control group, 73 subjects free from any kind of headache were included (HC). The presence of allodynia and sleep disturbances was assessed by a set of semi-structured questions. Chi-square test was applied to compare frequencies among groups. Sleep quality was worse among migraineurs with respect to controls for each sleep item analysed. This difference was significant for all items but one (i.e. frequency in drug use to induce sleep). The frequency of sleep disturbances was higher than in controls in both allodynic and non-allodynic migraineurs, although statistical analysis showed that all these differences were still significant in allodynic migraineurs (also in this case for all the sleep items but one, i.e. frequency in drug use to induce sleep), whilst non-allodynic migraineurs were significantly different from controls only for one item (frequency of initial insomnia). These results suggest that allodynia is strongly related to sleep quality, in a bi-directional way: sleep disturbances may favour central sensitisation, and, in turn, allodynia may impair sleep.

Original languageEnglish
JournalNeurological Sciences
Volume31
Issue numberSUPPL.1
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Hyperalgesia
Sleep
Central Nervous System Sensitization
Migraine Disorders
Trigeminal Nuclei
Sleep Initiation and Maintenance Disorders
Chi-Square Distribution
Pharmaceutical Preparations
Headache
Control Groups
Skin

Keywords

  • Allodynia
  • Headache
  • Migraine
  • Sleep
  • Sleep quality

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)

Cite this

Lovati, C., D'Amico, D., Bertora, P., Raimondi, E., Rosa, S., Zardoni, M., ... Mariani, C. (2010). Correlation between presence of allodynia and sleep quality in migraineurs. Neurological Sciences, 31(SUPPL.1). https://doi.org/10.1007/s10072-010-0317-2

Correlation between presence of allodynia and sleep quality in migraineurs. / Lovati, C.; D'Amico, D.; Bertora, P.; Raimondi, E.; Rosa, S.; Zardoni, M.; Bussone, G.; Mariani, C.

In: Neurological Sciences, Vol. 31, No. SUPPL.1, 06.2010.

Research output: Contribution to journalArticle

Lovati, C, D'Amico, D, Bertora, P, Raimondi, E, Rosa, S, Zardoni, M, Bussone, G & Mariani, C 2010, 'Correlation between presence of allodynia and sleep quality in migraineurs', Neurological Sciences, vol. 31, no. SUPPL.1. https://doi.org/10.1007/s10072-010-0317-2
Lovati, C. ; D'Amico, D. ; Bertora, P. ; Raimondi, E. ; Rosa, S. ; Zardoni, M. ; Bussone, G. ; Mariani, C. / Correlation between presence of allodynia and sleep quality in migraineurs. In: Neurological Sciences. 2010 ; Vol. 31, No. SUPPL.1.
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