Possible relationships were investigated among clinical symptomatology, skin-reactions and RAST to some house dust mites, respectively defined as 'Major' (Dermatophagoides pteronyssinus and D. farinae) or 'Minor' (Tyrophagus putrescentiae; Glycyphagus domesticus; Acarus siro). 30 of the 45 tested patients showed a positive skin reaction, in different degrees, to all 5 species of mites; RAST was positive in 18 (60%) for the 'Major' and only in 7 (23%) for the G.d. among 'Minor' mites. Identical results have been achieved with the A. fraction obtained from the total extract of the 'Minor' by gel-filtration on Sephadex G25 (negative B and C fractions). The P-K test shows some degree of agreement with skin-reactions, rather than to RAST. The results of this investigation (which is still in course) cannot be univocally interpreted: great importance should be referred to extract purification and standardization.
|Translated title of the contribution||Correlation between skin-tests and RAST in the diagnosis of sensitization to some house dust mites|
|Number of pages||6|
|Journal||Folia Allergologica et Immunologica Clinica|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Immunology and Allergy