CORRELAZIONE TRA TESTS CUTANEI E RAST NELLA DIAGNOSTICA DELLE SENSIBILIZZAZIONI AD ALCUNI ACARI DOMESTICI

Translated title of the contribution: Correlation between skin-tests and RAST in the diagnosis of sensitization to some house dust mites

A. C. Negrini, O. Maddaluno, A. R. Sementa, E. Lassalaz

Research output: Contribution to journalArticlepeer-review

Abstract

Possible relationships were investigated among clinical symptomatology, skin-reactions and RAST to some house dust mites, respectively defined as 'Major' (Dermatophagoides pteronyssinus and D. farinae) or 'Minor' (Tyrophagus putrescentiae; Glycyphagus domesticus; Acarus siro). 30 of the 45 tested patients showed a positive skin reaction, in different degrees, to all 5 species of mites; RAST was positive in 18 (60%) for the 'Major' and only in 7 (23%) for the G.d. among 'Minor' mites. Identical results have been achieved with the A. fraction obtained from the total extract of the 'Minor' by gel-filtration on Sephadex G25 (negative B and C fractions). The P-K test shows some degree of agreement with skin-reactions, rather than to RAST. The results of this investigation (which is still in course) cannot be univocally interpreted: great importance should be referred to extract purification and standardization.

Translated title of the contributionCorrelation between skin-tests and RAST in the diagnosis of sensitization to some house dust mites
Original languageItalian
Pages (from-to)521-526
Number of pages6
JournalFolia Allergologica et Immunologica Clinica
Volume25
Issue number6
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Immunology and Allergy

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