Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia

Giovanni Cioni, Barbara Bertuccelli, Antonio Boldrini, Raffaello Canapicchi, Barbara Fazzi, Andrea Guzzetta, Eugenio Mercuri

Research output: Contribution to journalArticle

Abstract

Aim - To evaluate the correlation between visual function and neurodevelopmental outcome in children with periventricular leucomalacia at 1 and 3 years. Method - Visual acuity, visual field, ocular motility, and optokinetic nystagmus were tested in 29 infants with periventricular leucomalacia by brain magnetic resonance imaging. All infants also had a structured neurological examination and a Griffiths developmental assessment. Results - 21 of the infants showed at least one abnormality of visual function. The degree of visual impairment-that is, the number of visual tests showing abnormal results-correlated well with the results on developmental assessment at both ages. Conclusion - Multivariate analysis showed that visual impairment was the most important variable in determining the neurodevelopmental scores of these infants, more than their motor disability and the extent of their lesions on magnetic resonance imaging.

Original languageEnglish
JournalArchives of Disease in Childhood: Fetal and Neonatal Edition
Volume82
Issue number2
Publication statusPublished - 2000

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Periventricular Leukomalacia
Magnetic Resonance Imaging
Vision Disorders
Optokinetic Nystagmus
Neurologic Examination
Visual Fields
Visual Acuity
Multivariate Analysis
Brain

Keywords

  • Developmental score
  • Magnetic resonance imaging
  • Periventricular leucomalacia
  • Vision

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia. / Cioni, Giovanni; Bertuccelli, Barbara; Boldrini, Antonio; Canapicchi, Raffaello; Fazzi, Barbara; Guzzetta, Andrea; Mercuri, Eugenio.

In: Archives of Disease in Childhood: Fetal and Neonatal Edition, Vol. 82, No. 2, 2000.

Research output: Contribution to journalArticle

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AU - Canapicchi, Raffaello

AU - Fazzi, Barbara

AU - Guzzetta, Andrea

AU - Mercuri, Eugenio

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