Correlation of angiographic and sequential CT findings in patients with evolving cerebral infarction

L. Bozzao, S. Bastianello, L. M. Fantozzi, U. Angeloni, C. Argentino, C. Fieschi

Research output: Contribution to journalArticle

Abstract

The usefulness of CT and angiography for predicting the final ischemic brain damage resulting from supratentorial ischemic stroke was evaluated in 36 patients. CT was performed within 4 hr and angiography within 6 hr after the onset of symptoms. CT was used to assess the site and size of parenchymal brain damage and angiography was used to evaluate the cerebral circulation. A 3-month follow-up CT study was used to determine the site and size of final ischemic damage. Angiography was normal in six patients and showed complete occlusion in 30. Angiographic findings in patients with arterial occlusion were classified as either internal carotid artery occlusion or middle cerebral artery (MCA) occlusion. MCA occlusions were subdivided into occlusion before the origin of internal lenticulostriate arteries (type 1), occlusion beyond the origin of these branches (type 2), occlusion at the bifurcation of the main trunk (type 3), and occlusion of he peripheral branches (type 4). Collateral blood supply was also studied. Early CT findings were positive in 25 of 36 patients; the lentiform nucleus alone, the lentiform nucleus and the cortex, or only the cortex were involved. In all patients with positive early CT findings, angiography showed an arterial occlusion, often located in the main trunk of the MCA. Involvement of the lentiform nucleus on early CT was always seen in patients with internal carotid artery or type 1 MCA occlusion. Involvement of the lentiform nucleus was also observed in some, but not all, patients with types 2 and 3 MCA occlusion, depending on the site of the external lenticulostriate arteries. A lesion in the lentiform nucleus was evident on 3-month follow-up scans in all patients who had injury of the lentiform nucleus or lentiform nucleus and cortex on early CT scans. The condition of the cerebral cortex was found to be related to the development of collateral blood supply. In patients with a normal early CT scan, angiography was normal or indicated occlusion of two or three peripheral branches, and the final CT damage was always limited in extent. When CT was performed during a very early phase of supratentorial ischemic stroke, the site and size of arterial occlusion could be documented and final brain damage could be predicted.

Original languageEnglish
Pages (from-to)1215-1222
Number of pages8
JournalAmerican Journal of Neuroradiology
Volume10
Issue number6
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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    Bozzao, L., Bastianello, S., Fantozzi, L. M., Angeloni, U., Argentino, C., & Fieschi, C. (1989). Correlation of angiographic and sequential CT findings in patients with evolving cerebral infarction. American Journal of Neuroradiology, 10(6), 1215-1222.