Correlation of deglutition in subacute ischemic stroke patients with peripheral blood adaptive immunity: Essential amino acid improvement

Roberto Aquilani, Benevolo Emilio, Maurizia Dossena, Paola Baiardi, Amidio Testa, Federica Boschi, Simona Viglio, Paolo Iadarola, Evasio Pasini, Manuela Verri

Research output: Contribution to journalArticle

Abstract

We aimed to document in stroke patients peripheral blood immune cell profiles, their relations with neuro-functional tests, and any possible influence of supplemented essential amino acids (EAAs) may have on both the immune system and the relationship of the latter with neuro-function. Forty-two dysphagic stroke patients (27 men; 71±9 years) underwent bio-humoral measurements, neuro-functional tests, including Functional Independence Measure (FIM) and Dysphagia Outcome and Severity Scale (DOSS), and were randomized to receive EAAs 8 g/d (EAA group) or isocaloric maltodextrin (placebo group). At discharge all measurements were repeated 38±1 days after randomization. At admission, total white cell (TWC), neutrophil (N), and lymphocyte (Lymph) counts were normal and the N/Lymph ratio was higher than normal values (

Original languageEnglish
Pages (from-to)576-583
Number of pages8
JournalInternational Journal of Immunopathology and Pharmacology
Volume28
Issue number4
DOIs
Publication statusPublished - Dec 1 2015

Keywords

  • dysphagia
  • essential amino acids
  • immune system
  • sub-acute stroke

ASJC Scopus subject areas

  • Pharmacology
  • Immunology
  • Immunology and Allergy

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