Correlation of dual X-ray absorptiometry and quantitative ultrasound with structural and strength modifications in ovariectomized rat femurs

Gianluca Giavaresi, M. Fini, P. Torricelli, F. De Terlizzi, S. Gnudi, R. Giardino

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Abstract

Background. Structural and strength modifications occurred in cortical and cancellous femoral bone of ovariectomized rats were investigated by comparing dual X-ray absorptiometry and quantitative ultrasound with biomechanics and histomorphometry. Methods. These measurements were performed in 30 femurs, dissected from normal (baseline), ovariectomized (OVX) and sham-operated (sham) Sprague Dawley rats aged 14 months. Results. Femoral densitometric data showed a decrease in the whole femur BMDtot (-9%, ptot (-12%, pcondyle (-11%, pcondyle results: different structural and mechanical properties seem to justify the possible different sensitivity of the two methods.

Original languageEnglish
Pages (from-to)35-42
Number of pages8
JournalItalian Journal of Mineral and Electrolyte Metabolism
Volume15
Issue number1-4
Publication statusPublished - 2001

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Keywords

  • Bone density
  • Densitometry, X ray
  • Femur
  • Rats
  • Ultrasonography

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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